ChemicalBook--->CAS DataBase List--->574013-68-6

574013-68-6

574013-68-6 Structure

574013-68-6 Structure
IdentificationBack Directory
[Name]

(E)-methyl 3-(3-(N-(4-styrylbenzyl)cyclohexanecarboxamido)phenyl)acrylate
[CAS]

574013-68-6
[Synonyms]

FEXARENE
Methyl 3-(3-(N-(4-(styryl)benzyl)cyclohexanecarboxamido)phenyl)acrylate
(E)-methyl 3-(3-(N-(4-styrylbenzyl)cyclohexanecarboxamido)phenyl)acrylate
2-Propenoic acid, 3-[3-[(cyclohexylcarbonyl)[[4-(2-phenylethenyl)phenyl]methyl]amino]phenyl]-, methyl ester
[Molecular Formula]

C32H33NO3
[MDL Number]

MFCD29035145
[MOL File]

574013-68-6.mol
[Molecular Weight]

479.61
Hazard InformationBack Directory
[Description]

Fexarene is a non-steroidal FXR agonist.
[Uses]

Fexarene is a potent and selective nonsteroidal Farnesoid X Receptor (FXR) agonist with an EC50 of 36 nM. Fexarene can be used in studies of cholesterol and bile acid metabolism[1].
[References]

[1] Nicolaou KC, et al. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Org Biomol Chem. 2003 Mar 21;1(6):908-20. PMID:12929628
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