| Identification | Back Directory | [Name]
β-Cembrenediol | [CAS]
57605-81-9 | [Synonyms]
β-Cembrenediol
b-Cembrenediol
beta-CeMbrenediol
Cembratriene-4,6-diol
(+)-β-Cembratrienediol
β-4,8,13-Duvatriene-1,3-diol
(1S,2E,4R,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol
(1E,3R,5R,6E,10E,14S)-14-Isopropyl-3,7,11-trimethylcyclotetradeca-1,6,10-triene-3,5-diol
(1R,3R,4E,8E,12S,13E)-1,5,9-Trimethyl-12-(1-methylethyl)-4,8,13-cyclotetradecatriene-1,3-diol
4,8,13-Cyclotetradecatriene-1,3-diol, 1,5,9-trimethyl-12-(1-methylethyl)-, (1R,3R,4E,8E,12S,13E)- | [Molecular Formula]
C20H34O2 | [MDL Number]
MFCD23699545 | [MOL File]
57605-81-9.mol | [Molecular Weight]
306.48 |
| Chemical Properties | Back Directory | [Melting point ]
106-112°C | [Boiling point ]
431.8±45.0 °C(Predicted) | [density ]
0.932±0.06 g/cm3(Predicted) | [storage temp. ]
Amber Vial, -20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.13±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Uses]
β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments. | [in vivo]
β-Cembrenediol (15 mg/kg; p.o.; daily for 8 weeks) shows anti-tumor activity in prostate cancer mice[2]. | Animal Model: | Male athymic nude mice (PC-3M PC cells)[2] | | Dosage: | 15 mg/kg | | Administration: | P.o.; daily for 8 weeks | | Result: | Significantly suppressed the development, extended the latency, and delayed the onset of the locoregional PC-3M cell tumor recurrence, reduced mice plasma total prostate-specific antigen and plasma kynurenine level. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
|