| Identification | Back Directory | [Name]
Cucurbitacin C | [CAS]
5988-76-1 | [Synonyms]
Cucurbitacin C
(10α,23E)-25-(Acetyloxy)-3β,16α,20-trihydroxy-9β-(hydroxymethyl)-19-norlanosta-5,23-diene-11,22-dione
19-Norlanosta-5,23-diene-11,22-dione, 25-(acetyloxy)-3,16,20-trihydroxy-9-(hydroxymethyl)-, (3α,9β,10α,16α,23E)- | [Molecular Formula]
C32H48O8 | [MDL Number]
MFCD30543614 | [MOL File]
5988-76-1.mol | [Molecular Weight]
560.73 |
| Chemical Properties | Back Directory | [Melting point ]
207-207.5 °C | [Boiling point ]
701.0±60.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [pka]
12.59±0.29(Predicted) | [InChIKey]
DGIGXLXLGBAJJN-UQMLAXSPNA-N |
| Hazard Information | Back Directory | [Uses]
Cucurbitacin C is a triterpenoid calabinoid that can be isolated from Cucurbitaceae plants. Cucurbitacin C has anti-cancer activity in vivo and in vitro. Cucurbitacin C can induce cell cycle arrest in G1 or G2/M phase and apoptosis by inhibiting Akt signaling[1]. | [Definition]
ChEBI: Cucurbitacin C is a cucurbitacin. | [References]
[1] Wu D, et al. In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber. Front Pharmacol. 2019 Nov 8;10:1287. DOI:10.3389/fphar.2019.01287 |
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