| Identification | Back Directory | [Name]
(S)-3-HYDROXYBUTYRIC ACID | [CAS]
6168-83-8 | [Synonyms]
(S)-3-Hydroxybutyrate
L-3-Hydroxybutyric acid
(S)-3-HYDROXYBUTYRIC ACID
(3S)-3-hydroxybutyric acid
(S)-3-Hydroxybutanoic acid
(S)-β-Hydroxybutanoic acid
(3S)-3-hydroxybutanoic acid
(S)-(+)-3-HYDROXYBUTYRIC ACID
[S,(+)]-3-Hydroxybutanoic acid
Butanoic acid, 3-hydroxy-, (3S)- | [EINECS(EC#)]
228-209-4 | [Molecular Formula]
C4H8O3 | [MDL Number]
MFCD00137685 | [MOL File]
6168-83-8.mol | [Molecular Weight]
104.1 |
| Chemical Properties | Back Directory | [Melting point ]
45-48 °C
| [alpha ]
25 º (C=6% IN H2O) | [Boiling point ]
269.2±0.0 °C(Predicted) | [density ]
1.195±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
solid | [pka]
4.36±0.10(Predicted) | [color ]
White | [Optical Rotation]
[α]20/D +25±1°, c = 6% in H2O | [Water Solubility ]
Water : 50 mg/mL (480.31 mM) | [BRN ]
1720567 | [InChI]
InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m0/s1 | [InChIKey]
WHBMMWSBFZVSSR-VKHMYHEASA-N | [SMILES]
C(O)(=O)C[C@@H](O)C |
| Hazard Information | Back Directory | [Uses]
(S)-3-Hydroxybutanoic acid is a metabolite and a disease marker of depression. 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low. | [Definition]
ChEBI: The S-enantiomer of 3-hydroxybutyric acid; a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C | [References]
[1] Khouri H, et al., Acetoacetate and d- and l-β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells. Am J Physiol Cell Physiol. 2024 Jun 1;326(6):C1710-C1720. DOI:10.1152/ajpcell.00718.2023 |
|
|