| Identification | More | [Name]
ETHYLTHIOUREA | [CAS]
625-53-6 | [Synonyms]
1-ETHYL-2-THIOUREA
1-ETHYLTHIOUREA
ETHYLTHIOUREA
N-ETHYL-2-THIOUREA
N-ETHYLTHIOUREA
N-ETHYLTHIOUREA, POLYMER-BOUND
1-ethyl-2-thio-ure
ethyl-2-thiourea
Ethylthiourea,99%
Thiourea, ethyl- | [EINECS(EC#)]
210-899-3 | [Molecular Formula]
C3H8N2S | [MDL Number]
MFCD00004939 | [Molecular Weight]
104.17 | [MOL File]
625-53-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
108-110 °C(lit.) | [Boiling point ]
132 °C | [density ]
1.055 (estimate) | [refractive index ]
1.5500 (estimate) | [storage temp. ]
Store at RT | [solubility ]
methanol: soluble25mg/mL, clear, colorless | [form ]
Solid | [pka]
14.97±0.29(Predicted) | [color ]
White to Off-White | [Water Solubility ]
Soluble in water (24g/L). | [BRN ]
1699551 | [InChI]
InChI=1S/C3H8N2S/c1-2-5-3(4)6/h2H2,1H3,(H3,4,5,6) | [InChIKey]
GMEHFXXZSWDEDB-UHFFFAOYSA-N | [SMILES]
N(CC)C(N)=S | [CAS DataBase Reference]
625-53-6(CAS DataBase Reference) | [EPA Substance Registry System]
Ethylthiourea (625-53-6) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R25:Toxic if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
YT3700000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [Safety Profile]
Poison by ingestion.
SYN: 1-ETHYLTHIOUREA
Experimental teratogenic effects. Mutation
data reported. When heated to decomposition it emits toxic fumes of Sox and NOx. | [Hazardous Substances Data]
625-53-6(Hazardous Substances Data) | [Toxicity]
mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981. |
| Hazard Information | Back Directory | [Uses]
N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides | [Definition]
ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea. | [General Description]
N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described. | [reaction suitability]
reagent type: catalyst
reagent type: chelator | [Biological Activity]
Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). | [Purification Methods]
Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.] |
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