| Identification | Back Directory | [Name]
KUWANONC | [CAS]
62949-79-5 | [Synonyms]
Kuwanon
KUWANONC
Mulberrin
Mulberrin (Kuwanon C)
Mulberrin (Synonyms: Kuwanon C)
3,8-Bis(3-methyl-2-butenyl)-2',4',5,7-tetrahydroxyflavone
2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-enyl)chromen-4-one
2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-buten-1-yl)-
2-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-8-((Z)-3-methyl-but-2-enyl)-3-(3-methyl-but-2-enyl)-1-benzopyran-4-one | [Molecular Formula]
C25H26O6 | [MDL Number]
MFCD20274692 | [MOL File]
62949-79-5.mol | [Molecular Weight]
422.47 |
| Chemical Properties | Back Directory | [Melting point ]
153-156 °C | [Boiling point ]
657.7±55.0 °C(Predicted) | [density ]
1.290±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO : 100 mg/mL (236.70 mM; Need ultrasonic) | [form ]
powder | [pka]
6.70±0.40(Predicted) | [color ]
Yellow | [InChI]
InChI=1S/C25H26O6/c1-13(2)5-8-17-20(28)12-21(29)22-23(30)18(9-6-14(3)4)24(31-25(17)22)16-10-7-15(26)11-19(16)27/h5-7,10-12,26-29H,8-9H2,1-4H3 | [InChIKey]
UWQYBLOHTQWSQD-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(O)C=C2O)OC2=C(C/C=C(/C)\C)C(O)=CC(O)=C2C(=O)C=1C/C=C(/C)\C |
| Hazard Information | Back Directory | [Description]
Mulberrin (Mul) is a critical component of the traditional Chinese medicine Romulus Mori, which has antioxidant and anti-inflammatory properties. Studies have indicated that Mul promotes Nrf-2/HO-1 signaling to attenuate oxidative damage, inflammation accumulation, and myocardial apoptosis. In addition, Mul confers protection against hepatic fibrosis by improving Nrf2 nuclear translocation[1]. | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from mulberry branches. | [Uses]
Mulberrin is has potential as a hepatoprotective nutraceutical compound. It can also be used for antiviral, antibacterial, and anti-inflammatory properties. | [References]
[1] Siwen Li . “Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.” Comparative Biochemistry and Physiology C-toxicology Pharmacology 273 (2023): Article 109734.
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