| Identification | Back Directory | [Name]
mulberrofuran G | [CAS]
87085-00-5 | [Synonyms]
albanol A
mulberrofuran G
Mulberrofuran G（(+)-Albanol A,Albanol A）
3aH-Benzo[3,4][2]benzopyrano[1,8-bc][1]benzopyran-4,11-diol, 8a-(2,4-dihydroxyphenyl)-1,8a,13b,13c-tetrahydro-6-(6-hydroxy-2-benzofuranyl)-2-methyl-, (3aS,8aS,13bS,13cR)- | [Molecular Formula]
C34H26O8 | [MDL Number]
MFCD31631870 | [MOL File]
87085-00-5.mol | [Molecular Weight]
562.57 |
| Chemical Properties | Back Directory | [Boiling point ]
695.1±55.0 °C(Predicted) | [density ]
1.484±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.87±0.60(Predicted) | [color ]
White to off-white | [LogP]
6.346 (est) |
| Hazard Information | Back Directory | [Uses]
Mulberrofuran G protects ischemic injury-induced cell death via inhibition of NOX4-mediated ROS generation and ER stress[1]. Mulberrofuran G shows moderate inhibiting activity of hepatitis B virus (HBV) DNA replication with IC50 of 3.99 μM[2]. | [target]
HBV | [IC 50]
NOX4 | [References]
[1] Hong S, Kwon J, Kim DW, Lee HJ, Lee D, Mar W. Mulberrofuran G Protects Ischemic Injury-induced Cell Death via Inhibition of NOX4-mediated ROS Generation and ER Stress.?Phytother Res. 2017;31(2):321-329. DOI:10.1002/ptr.5754
[2] Geng CA, Ma YB, Zhang XM, et al. Mulberrofuran G and isomulberrofuran G from Morus alba L.: anti-hepatitis B virus activity and mass spectrometric fragmentation.?J Agric Food Chem. 2012;60(33):8197-8202. DOI:10.1021/jf302639b |
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