| Identification | Back Directory | [Name]
Crenulatin | [CAS]
63026-02-8 | [Synonyms]
β-D-Glucopyranoside, 1,1-dimethyl-2-propen-1-yl | [Molecular Formula]
C11H20O6 | [MDL Number]
MFCD31747155 | [MOL File]
63026-02-8.mol | [Molecular Weight]
248.27 |
| Chemical Properties | Back Directory | [Boiling point ]
417.2±45.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.92±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Crenulatin is a gallotannin that can be isolated from Rhodiola rosea. Crenulatin can be used as a biomarker to identify potentially adulterated R. rosea products. Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, via regulating Fas/Bcl-2 expression and caspase-3 activity[1][2][3]. | [References]
[1] Marchev AS, et al. Authenticity and quality evaluation of different Rhodiola species and commercial products based on NMR-spectroscopy and HPLC. Phytochem Anal. 2020 Nov;31(6):756-769. DOI:10.1002/pca.2940
[2] W S Yu, et al. Polyphenols from Rhodiola crenulata. Planta Med. 1993 Feb;59(1):80-2. DOI:10.1055/s-2006-959610
[3] Qian R, et al. Dual-direction effect of crenulatin on apoptosis of cerebral microvascular endothelial cells and it's mechanism[J]. Chinese Journal of Pathophysiology, 2005: 2086-2090. |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|