| Identification | More | [Name]
(S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE | [CAS]
63126-47-6 | [Synonyms]
H-PRO-OL(ME)
H-S-PYR-MEOME
L-PROLINOL METHYL ETHER
O-METHYL-D-PROLINOL
O-METHYL-L-PROLINOL
PROLINOL-METHYL-ETHER
(S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE
(S)-2-(METHOXYMETHYL)PYRROLIDINE
(S)-2-(METHOXYMETHYL)-PYRROLIDINEMETHYL
(S)-2-PYRROLIDINEMETHYL-METHYL ETHER
SMP
(S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE, 99 %
(S)-(+)-2-(Methoxymethyl)pyrrplidine
PROLINOL-METHYL-ETHER, (S)-2-PYRROLIDINEMETHYL-METHYL ETHER, (S)-2-(METHOXYMETHYL)-PYRROLIDINEMETHYL
(S)-2-Pyrrolidinemethyl-methyl ether, (S)-2-(Methoxymethyl)-pyrrolidinemethyl
L-Prolinol-OMe
O-Methyl-L-prolinol, SMP | [Molecular Formula]
C6H13NO | [MDL Number]
MFCD00010408 | [Molecular Weight]
115.17 | [MOL File]
63126-47-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellow liquid | [Boiling point ]
62 °C40 mm Hg(lit.) | [density ]
0.933 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.446
| [Fp ]
114 °F
| [storage temp. ]
Store at 0-5°C | [solubility ]
sol H2O, ether, dichloromethane. | [form ]
Liquid | [pka]
10.01±0.10(Predicted) | [color ]
Clear colorless to yellow | [Optical Rotation]
[α]20/D +2.4°, c = 2 in benzene | [Sensitive ]
Air Sensitive | [BRN ]
3587324 | [InChI]
InChI=1S/C6H13NO/c1-8-5-6-3-2-4-7-6/h6-7H,2-5H2,1H3/t6-/m0/s1 | [InChIKey]
CHPRFKYDQRKRRK-LURJTMIESA-N | [SMILES]
N1CCC[C@H]1COC | [CAS DataBase Reference]
63126-47-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [F ]
3-9-34 | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to yellow liquid | [Uses]
(S)-(+)-2-(Methoxymethyl)pyrrolidine may be used to prepare planar chiral 2-phospha[3]ferrocenophanes. It may also be used as an organocatalyst in the cross-aldol reaction of dihydroxyacetone with p-nitrobenzaldehyde to form the corresponding polyol. SMP reacts with benzoylformic acid to form (S)-N-benzoylformyl-2-(methoxymethyl)-pyrrolidine. | [Application]
(S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE is used for chiral auxiliary; asymmetric syntheses with SMP enamines and SMP amides; asymmetric Birch
reductions; asymmetric Diels-Alder reactions. | [Definition]
ChEBI: (S)-2-(methoxymethyl)pyrrolidine is a member of the class of pyrrolidines in which the only substituent is a methoxymethyl group at position 2 (the S-enantiomer0. It is a member of pyrrolidines and an ether. | [Synthesis]
(S)-(+)-2-(methoxymethyl)pyrazolidine is an organic intermediate that can be prepared from (S)-proline reduction to prepare (S)-2-hydroxymethylpyrrolidine, then formylated and methylated to prepare (S)-(-)-2-(methoxymethyl)-1-pyrrolidinecarboxaldehyde, | [storage]
(S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE stores at 0-4 °C under an argon atmosphere. |
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