| Identification | More | [Name]
METHYL 4-FLUOROBENZOYLACETATE | [CAS]
63131-29-3 | [Synonyms]
3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER
4-FLUOROBENZOYLACETIC ACID METHYL ESTER
METHYL 3-(4-FLUOROPHENYL)-3-OXOPROPIONATE
METHYL 4-FLUOROBENZOYLACETATE
Methyl4-fluorobenzoylacetate,95%
3-(4-fluorophenyl)-3-oxopropionic aicd methyl ester
Methyl p-fluorobenzoylacetate, 99%
3-(p-Fluorophenyl)-3-oxopropionic acid methyl ester
3-Oxo-3-(4-fluorophenyl)propanoic acid methyl ester
3-Oxo-3-(4-fluorophenyl)propionic acid methyl ester
β-Oxo-4-fluorobenzenepropionic acid methyl ester | [EINECS(EC#)]
263-889-6 | [Molecular Formula]
C10H9FO3 | [MDL Number]
MFCD00000355 | [Molecular Weight]
196.18 | [MOL File]
63131-29-3.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow liquid | [Boiling point ]
91°C/5mm | [density ]
1.228 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.521(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Liquid | [pka]
9.80±0.25(Predicted) | [color ]
Clear colorless to dark yellow | [BRN ]
3050469 | [InChI]
1S/C10H9FO3/c1-14-10(13)6-9(12)7-2-4-8(11)5-3-7/h2-5H,6H2,1H3 | [InChIKey]
HGLVYXXPRSNKQN-UHFFFAOYSA-N | [SMILES]
COC(=O)CC(=O)c1ccc(F)cc1 | [CAS DataBase Reference]
63131-29-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29183000 | [Storage Class]
10 - Combustible liquids |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow liquid | [Uses]
Methyl 4-fluorobenzoylacetate was used in the synthesis of:
- 3-amino-4-(-4-fluoro-phenyl)furazan
- series of substituted coumarin derivatives, potential 5-lipoxygenase inhibitors
| [Synthesis]
Anhydrous tetrahydrofuran (540 mL), dimethyl carbonate (235.2 g, 2.61 mol) and sodium hydrogen (130.5 g, 3.263 mol, 60%) were added to a dry reaction flask then the mixture was heated to reflux, and a solution of anhydrous tetrahydrofuran (180 mL) of p |
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