| Identification | Back Directory | [Name]
Azaphenonxazine dihydrochloride Monohydrate | [CAS]
63302-99-8 | [Synonyms]
Azafen dihydrochloride Monohydrate
Azaphen (dihydrochloride Monohydrate)
Pipofezin dihydrochloride Monohydrate
Pipofezine dihydrochloride Monohydrate
Azaphenonxazine dihydrochloride Monohydrate
5-Methyl-3-(4-methyl-1-piperazinyl)-5H-pyridazino[3,4-b][1,4]benzoxazine dihydrochloride monohydrate
AZAFEN DIHYDROCHLORIDE MONOHYDRATE;PIPOFEZIN DIHYDROCHLORIDE MONOHYDRATE;PIPOFEZINE DIHYDROCHLORIDE MONOHYDRATE;AZAPHENONXAZINE DIHYDROCHLORIDE MONOHYDRATE | [Molecular Formula]
C16H23Cl2N5O2 | [MDL Number]
MFCD00220368 | [MOL File]
63302-99-8.mol | [Molecular Weight]
388.292 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Water: ≥ 100 mg/mL (257.54 mM); DMSO: 1 mg/mL (2.58 mM) | [form ]
Solid | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin.
IC50 Value:
Target: SSRIs
Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. | [References]
[1] Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. PMID:16281382
[2] Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. PMID:557800
[3] Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. PMID:1112390
[4] Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6. PMID:4450998 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|