| Identification | Back Directory | [Name]
1',3'-bis[1,2-diMyristoyl-sn-glycero-3-phospho]-sn-glycerol (aMMoniuM salt) | [CAS]
63988-20-5 | [Synonyms]
14:0 Cardiolipin (ammonium salt)
Tetramyristoylcardiolipin (ammonium salt)
1',3'-bis[1,2-diMyristoyl-sn-glycero-3-phospho]-sn-glycerol (aMMoniuM salt) | [Molecular Formula]
C65H129NO17P2 | [MDL Number]
MFCD22495252 | [MOL File]
63988-20-5.mol | [Molecular Weight]
1258.68 |
| Chemical Properties | Back Directory | [Melting point ]
181-182 °C | [storage temp. ]
-20°C | [solubility ]
Chloroform: 10 mg/ml; Methanol: soluble with slight heating | [form ]
A solid |
| Hazard Information | Back Directory | [Uses]
1'',?3''-1'',?3''-?bis[1,?2-?Dimyristoyl-?sn-?glycero-?3-?phospho]?-?glycerol Ammonium Salt is a PEGylated liposome-encapsulated glycopeptide antibiotic for treatment of bacterial infections. | [Biological Activity]
Cardiolipin participates in proton uptake pathway and also maintains the structure of enzymes involved. Cardiolipin maintains the mitochondrial functionmembrane potential and structural support for the inner mitochondrial membrane and proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemiahypothyroidismagingheart failure and cardioskeletal myopathy.) Cardiolipin can form micelles/vesicles naturally.''TMCL (1,1μ,2,2μ-tetramyristoyl cardiolipin) bilayers are useful in generating multilamellar vesicles. Defects in the cardiolipin metabolic associated with Barth syndrome patients. Liposomes of TMCL with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and cholesterol are potential drug-delivery systems. TMCL displays temperature dependent thermotropic phase transitions. |
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Energy Chemical
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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Merck KGaA
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Creative Enzymes
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