| Identification | Back Directory | [Name]
1H-PeriMidine,2-(4-broMophenyl)-2,3-dihydro- | [CAS]
64369-13-7 | [Synonyms]
HepIn-13
Hepln-13
1H-PeriMidine,2-(4-broMophenyl)-2,3-dihydro-
2-(4-Bromo-phenyl)-2,3-dihydro-1H-perimidine
potent,non-toxic,overexpression-relevant,phenotypes,orally,inhibit,Hepln-13,prostate,cancer,Inhibitor | [Molecular Formula]
C17H13BrN2 | [MDL Number]
MFCD01038678 | [MOL File]
64369-13-7.mol | [Molecular Weight]
325.2 |
| Hazard Information | Back Directory | [Uses]
Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 μM. Hepln-13 can be used for the research of metastatic prostate cancer[1]. | [in vivo]
HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis[1]. | [References]
[1] Tang X, et al. Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis. Oncotarget. 2014;5(5):1352-1362. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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