| Identification | More | [Name]
L-Lysine dihydrochloride | [CAS]
657-26-1 | [Synonyms]
H-LYS-OH 2HCL
L-2,6-DIAMINOHEXANOIC ACID DIHYDROCHLORIDE
L-(+)-LYSINE DIHYDROCHLORIDE
L-LYSINE DIHYDROCHLORIDE
(S)-2,6-Diaminohexanoic acid dihydrochloride
H-Lys-OH·2HCI
DL-sercine methyl ester hydrochloride
L-Lisine dihydrochloride
L-LYSINE DIHYDROCHLORIDE 99%
L-LYSINE 2HCL
Lysine dihydrochloride
L-Lysine-alpha-15N2HCl
L-Lysine-UL-13C62HCl
L-Lysine dihydrate
L-LysineHCl-6-13C
L-Lysine-UL-13C6HCl
(2S)-2,6-Diaminohexanoic acid dihydrochloride
L-Lysine·dihydrochloric acid | [EINECS(EC#)]
211-518-3 | [Molecular Formula]
C6H16Cl2N2O2 | [MDL Number]
MFCD00066389 | [Molecular Weight]
219.11 | [MOL File]
657-26-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to very light yellow crystalline powder | [Melting point ]
200-206 °C(lit.)
| [alpha ]
14 º (c=2, water 18 ºC) | [refractive index ]
15 ° (C=2, H2O) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Crystalline Powder | [color ]
White to very light yellow | [Water Solubility ]
Soluble in water (100 mg/ml). | [Sensitive ]
Hygroscopic | [Merck ]
14,5636 | [BRN ]
4539715 | [InChI]
InChI=1/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/s3 | [InChIKey]
JBBURJFZIMRPCZ-WHWWGIJDNA-N | [SMILES]
[C@@H](N)(C(=O)O)CCCCN.Cl.Cl |&1:0,r| | [CAS DataBase Reference]
657-26-1(CAS DataBase Reference) | [EPA Substance Registry System]
657-26-1(EPA Substance) | [CAS Number Unlabeled]
657-26-1 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
29224190 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
white to very light yellow crystalline powder | [Uses]
Synthesis of hyperbranched polylysine using the N-hydroxysuccinimide ester of L-lysine dihydrochloride as AB 2 building block. The histidine and lysine standards were prepared from L-histidine monohydro- chloride and L-lysine dihydrochloride respectively. L-Homocitrulline-The copper complex was prepared from L-lysine dihydrochloride in 80 to 86 per cent yields. | [Biological Activity]
L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies. | [Synthesis]
L-lysine dihydrochloride is an organic intermediate that can be obtained from Boc-Lys-OH as a feedstock by removing the protective groups. HCl (4 M in dioxane, 2.5 mL, 10.0 mmol, 10.0 equiv) was added to a solution of Boc-Lys-OH (297 mg, 1.00 mmol) in MeO | [Purification Methods]
Crystallise it from MeOH, in the presence of excess HCl, by adding diethyl ether. [Yoneya J Biochem (Tokyo) 38 343 1951, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.] |
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