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663599-04-0

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663599-04-0 Structure

663599-04-0 Structure
IdentificationBack Directory
[Name]

DMAC-PDB
[CAS]

663599-04-0
[Synonyms]

DMAC-PDB
Butanoic acid, 4-[[5-[(dimethylamino)carbonyl]-2-pyridinyl]dithio]-
[Molecular Formula]

C12H16N2O3S2
[MDL Number]

MFCD34469570
[MOL File]

663599-04-0.mol
[Molecular Weight]

300.4
Chemical PropertiesBack Directory
[Boiling point ]

530.3±50.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

4.59±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Wayne Charles Widdison, et al. Cross-linkers with high reactivity and solubility and their use in the preparation of conjugates for targeted delivery of small molecule drugs. WO2004016801A2
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