ChemicalBook--->CAS DataBase List--->66648-35-9

66648-35-9

66648-35-9 Structure

66648-35-9 Structure
IdentificationBack Directory
[Name]

Z-GLY-PRO-ARG-PNA
[CAS]

66648-35-9
[Synonyms]

Z-GPR-pNA
Z-GLY-PRO-ARG-PNA
Cbz-Gly-Pro-Arg-pNA
carbobenzoxyglycyl-prolyl-arginine-4-nitroanilide
L-Argininamide, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-N-(4-nitrophenyl)- (9CI)
[Molecular Formula]

C27H34N8O7
[MDL Number]

MFCD00083723
[MOL File]

66648-35-9.mol
[Molecular Weight]

582.61
Chemical PropertiesBack Directory
[density ]

1.439±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

-20°C
[solubility ]

methanol: 20mg/mL, clear, colorless to light yellow
[form ]

powder
[pka]

11.344±0.46(predicted)
[Sequence]

{Z-Gly}-Pro-Arg-{pNA}
[InChIKey]

FPMAXHHYPVIJMC-VROPFNGYSA-N
[SMILES]

CC(O)=O.NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)OCc2ccccc2)C(=O)Nc3ccc(cc3)[N+]([O-])=O
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Z-Gly-Pro-Arg p-nitroanilide acetate salt has been used as a substrate in prostate-specific antigen (PSA) activation protease assay for determining enterokinase-PSA-trypsin (EK-PSA-TRP) activity and to perform kinetic experiments. It has also been used as a substrate to measure the pancreatic trypsin activity chromogenically.
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