| Identification | Back Directory | [Name]
Z-GLY-GLY-LEU-AMC | [CAS]
97792-39-7 | [Synonyms]
Z-GGL-AMC
Z-GLY-GLY-LEU-AMC
CBZ-Gly-Gly-Leu-AMC
Proteasome Substrate
PROTEASOME SUBSTRATE V, FLUOROGENIC
7-(N-benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin
7-(Nα-benzyloxycarbonyl-glycylglycyl-L-leucyl)amino-4-methylcoumarin
N-[(Phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide
L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
Carbobenzoxy-Gly-Gly-Leu-7-amido-4-methylcoumarin, benzyloxycarbonyl-glycyl-glycyl-leucyl-7-amido-4-methylcoumarin | [Molecular Formula]
C28H32N4O7 | [MDL Number]
MFCD00152029 | [MOL File]
97792-39-7.mol | [Molecular Weight]
536.58 |
| Hazard Information | Back Directory | [Uses]
Z-GGL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 20S proteasome. It is a sensitive fluorogenic substrate for subtilisins BPN'' and Carlsberg. | [Biological Activity]
Z-Gly-Gly-Leu-7-amido-4-methylcoumarin (Z-Gly-Gly-Leu-AMC) is a fluorogenic peptide th at is used in analysis of protease and peptidase activity of proteasomes. Z-GGL-AMC has been noted as a particular substrate for chymotrypsin-like activity. It has low solubility and precipitates at 100μM. |
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