ChemicalBook--->CAS DataBase List--->67254-28-8

67254-28-8

67254-28-8 Structure

67254-28-8 Structure
IdentificationBack Directory
[Name]

1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT
[CAS]

67254-28-8
[Synonyms]

DOPG
DOPG-Na
DOPG Sodium Salt
18:1 (Delta9-Cis) PG
PG(18:1(9Z)/18:1(9Z))
18:1 TRANS PG (SODIUM SALT)
L-A-phosphatidyl-dl-glycerol
L-α-Phosphatidyl-DL-glycerol
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-RA
L-α-Phosphatidyl-DL-glycerol, dioleoyl
Dioleoyl phosphatidylglycerole sodium salt
1,2-Dioleoyl-sn-glycero-3-PG (sodium salt)
L-A-PHOSPHATIDYL-DL-GLYCEROL, DIOLEOYL*S ODIUM
l-α-phosphatidyl-dl-glycerol, dioleoyl sodium salt
L-ALPHA-PHOSPHATIDYL-DL-GLYCEROL, DIOLEOYL SODIUM SALT
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-RAC-GLYCEROL SODIUM SALT
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Sal
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
Sodium (R)-2,3-Bis(oleoyloxy)propyl (2,3-Dihydroxypropyl) Phosphate
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt(DOPG)
1,2-DIELAIDOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)] (SODIUM SALT)
1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt
1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT
1, 2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol),Dioleoyl Phosphatidylglycerole
L-α-Phosphatidyl-DL-glycerol, dioleoyl, L-α-Phosphatidyl-DL-glycerol, dioleoyl sodium salt
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodiuM salt, solution, 10 Mg/ML in chloroforM
(9Z)-9-Octadecenoic acid 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt
[EINECS(EC#)]

200-663-8
[Molecular Formula]

C42H78NaO10P
[MDL Number]

MFCD00070069
[MOL File]

67254-28-8.mol
[Molecular Weight]

797.03
Chemical PropertiesBack Directory
[Fp ]

>200℃
[storage temp. ]

−20°C
[solubility ]

Chloroform: 2 mg/ml
[form ]

solution
[color ]

White to Almost white
[biological source]

synthetic
[InChIKey]

IUVFCFQZFCOKRC-PDSLQGCUSA-M
[SMILES]

[C@H](COC(=O)CCCCCCC/C=C\CCCCCCCC)(OC(=O)CCCCCCC/C=C\CCCCCCCC)COP(O)(=O)OCC(O)CO.[NaH] |&1:0,r|
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-38-40-48/20/22-67-36/38-20-63
[Safety Statements ]

36/37-26
[RIDADR ]

UN 1888 6.1/PG 3
[WGK Germany ]

3
[HS Code ]

2919.90.5050
Hazard InformationBack Directory
[Description]

1,2-Dioleoyl-sn-glycero-3-PG (DOPG) is a phospholipid containing the long-chain (18:1) fatty acid oleic acid (Item No. 90260) inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other artificial membranes.
[Uses]

1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) is an analog of 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) (D525495) which forms lipid bilayers. In the high temperature phase, the conformation of the chains is liquid-like. In the low temperature phases, the chains are stiff and parallel and they interdigitate.
[General Description]

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane?bilayers. It has three-carbon backbone of glycerol, two long-chain?fatty acids,?esterified to?hydroxyl groups on carbons 1 and 2 of the glycerol and?phosphoric acid?esterified to the C3?hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG?has two hydroxyl groups in its head group. It is an anionic lipid.
[Biochem/physiol Actions]

Remodeling of diacylphosphatidylglycerols by transesterification was studied in a phosphatidylglycerol-deficient microbe grown with exogenous DOPG.
[References]

[1] TOMOYOSHI TAKAHASHI. Multiple membrane interactions and versatile vesicle deformations elicited by melittin.[J]. Toxins, 2013: 637-664. DOI: 10.3390/toxins5040637
[2] CíNTIA C. VEQUI-SUPLICY . Vesicles with charged domains[J]. Biochimica et biophysica acta. Biomembranes, 2010, 1798 7: Pages 1338-1347. DOI: 10.1016/j.bbamem.2009.12.023
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