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63-89-8

63-89-8 Structure

63-89-8 Structure
IdentificationMore
[Name]

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
[CAS]

63-89-8
[Synonyms]

1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
16:0 PC
B,G-DIPALMITOYL-L-A-LECITHIN
COLFOSCERIL PALMITATE
DIPALMITOYL-L-ALPHA-LECITHIN
DIPALMITOYL LECITHIN
DPPC
L-A-LECITHIN DIPALMITOYL
L-ALPHA-DIPALMITOYL PHOSPHATIDYLCHOLINE
L-ALPHA-LECITHIN, DIPALMITOYL
L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL
L-ALPHA-PHOSPHATIDYLCHOLINE, DIPALMITOYL (C16:0)
L-BETA,GAMMA-DIPALMITOYL-ALPHA-LECITHIN
1,2-dipalmitoyl-3-sn-phosphatidylcholine
1,2-dipalmitoyl-L-alpha-phosphatidylcholine
L-A-phosphatidylcholine dipalmitoyl*synthetic
(R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide
[EINECS(EC#)]

232-642-4
[Molecular Formula]

C40H80NO8P
[MDL Number]

MFCD00036903
[Molecular Weight]

734.04
[MOL File]

63-89-8.mol
Chemical PropertiesBack Directory
[Appearance]

white powder
[Melting point ]

229-229.5 °C
[alpha ]

D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[biological source]

synthetic
[Merck ]

14,2477
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
[InChIKey]

KILNVBDSWZSGLL-KXQOOQHDSA-N
[SMILES]

[C@@H](OC(=O)CCCCCCCCCCCCCCC)(COC(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C |&1:0,r|
[CAS DataBase Reference]

63-89-8(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H331-H336-H351-H361d-H372-H412
[Precautionary statements ]

P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29232000
[Storage Class]

11 - Combustible Solids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

TYLOXAPOL-->Hexadecanoic acid, 1,1'-[1-[[(2-oxido-1,3,2-dioxaphospholan-2-yl)oxy]methyl]-1,2-ethanediyl] ester-->[S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol-->2-Chloroethylphosphoric acid dichloride-->Choline glycerophosphate-->1,2-Dipalmitoyl-sn-glycerol-->Choline tosylate-->Palmitic acid-->Trimethylamine
[Preparation Products]

1,2-Dipalmitoyl-sn-glycero-3-phosphobutanol (sodium salt)
Hazard InformationBack Directory
[Description]

DPPC, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid containing the 16 carbon fatty acid/palmitic acid (16:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.
[Chemical Properties]

white powder
[Uses]

1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
[Definition]

ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
[General Description]

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
[Biochem/physiol Actions]

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
[Purification Methods]

It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.]
Spectrum DetailBack Directory
[Spectrum Detail]

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(63-89-8)1HNMR
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(63-89-8)13CNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

L-alpha-Dipalmitoyl phosphatidylcholine, 98%(63-89-8)
[Sigma Aldrich]

63-89-8(sigmaaldrich)
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