| Identification | Back Directory | [Name]
13',19'-Didehydro-19'-deoxy-28,44-dihydro-44-hydroxymicrococcin P | [CAS]
67401-56-3 | [Synonyms]
Brn 1070340
Micrococcin P1
MQGFYNRGFWXAKA-QMXXNAFJSA-N
13',19'-Didehydro-19'-deoxy-28,44-dihydro-44-hydroxymicrococcin P
Micrococcin p, 13',19'-didehydro-19'-deoxy-28,44-dihydro-44-hydroxy-
[2,4'-Bithiazole]-4-carboxamide, 2'-[(11S,14Z,21S,28S)-14-ethylidene-9,10,11,12,13,14,20,21,27,28-decahydro-28-[(1R)-1-hydroxyethyl]-11-[(1R)-1-hydroxyethyl]-21-(1-methylethyl)-9,12,19,26-tetraoxo-19H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazac... | [Molecular Formula]
C48H49N13O9S6 | [MDL Number]
MFCD32202742 | [MOL File]
67401-56-3.mol | [Molecular Weight]
1144.37 |
| Chemical Properties | Back Directory | [density ]
1.1650 (rough estimate) | [refractive index ]
1.6700 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
10.68±0.46(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Micrococcin P1 holds the remarkable position in antibiotic discovery as the first of the early antibiotics to be lost to science. Micrococcin P1 is a thiopeptide originally isolated from Micrococcus sp. by Su at Oxford in 1948. Later, Heatley and Doery purified micrococcin and defined its physico-chemical properties and activity. The producing strain was lost, causing a hiatus in research of this antibiotic family until the discovery of the related thiocillins in 1976. |
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