ChemicalBook--->CAS DataBase List--->69014-14-8

69014-14-8

69014-14-8 Structure

69014-14-8 Structure
IdentificationBack Directory
[Name]

TIOTIDINE
[CAS]

69014-14-8
[Synonyms]

TIOTIDINE
ICI-125211
1-cyano-3-[2-[(2-guanidinothiazol-4-yl)methylthio]ethyl]-2-methyl-guanidine
1-Methyl-2-cyano-3-[2-[2-(diaminomethyleneamino)thiazole-4-ylmethylthio]ethyl]guanidine
1-Methyl-2-cyano-3-[2-[[2-(diaminomethyleneamino)thiazole-4-yl]methylthio]ethyl]guanidine
N-[2-[[[2-[(Aminoiminomethyl)amino]-4-thiazoyl]methyl]thio]ethyl]-N'-cyano-N''-methylguanidine
N-[2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]-N'-cyano-N''-methylguanidine
N'-Cyano-N-[2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]-N''-methylguanidine
1-cyano-3-[2-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-2-methylguanidine
1-[2-[[2-[bis(azanyl)methylideneamino]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-3-cyano-2-methyl-guanidine
[Molecular Formula]

C10H16N8S2
[MDL Number]

MFCD00661098
[MOL File]

69014-14-8.mol
[Molecular Weight]

312.42
Chemical PropertiesBack Directory
[Boiling point ]

490.1±55.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

Soluble to 10 mM in ethanol and to 100 mM in DMSO
[form ]

Powder
[pka]

pKa 6.80 (Uncertain)
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

Tiotidine is a potent human histamine H2 receptor antagonist.
[Definition]

ChEBI: 1-cyano-3-[2-[[2-(diaminomethylideneamino)-4-thiazolyl]methylthio]ethyl]-2-methylguanidine is a member of thiazoles.
[IC 50]

H2 Receptor: 7.3-7.8 (pA2); H3 Receptor: 4.8 (pA2)
[storage]

Store at RT
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