| Identification | More | [Name]
3-Methylaminopropionitrile | [CAS]
693-05-0 | [Synonyms]
3-METHYLAMINOPROPIONITRILE
BETA-METHYLAMINOPROPIONITRILE
N-METHYL-B-ALANINENITRILE
N-METHYL-BETA-ALANINENITRILE
(2-Cyanoethyl)methyl amine
(2-cyanoethyl)methylamine
(Methylamino)propionitrile
3-(methylamino)-propanenitril
3-(Methylamino)propanenitrile
3-(methylamino)-propionitril
3-(n-methylamino)propionitrile
ai3-26057
beta-methylaminopropionitril
n-(2-cyanoethyl)methylamine
n-(beta-cyanoethyl)methylamine
N-beta-Cyanoethylmethylamine
N-Methyl-beta-aminopropionitrile
Propionitrile, 3-(methylamino)-
3-(Methyl
n-methyl-β-alaninenitrile | [EINECS(EC#)]
211-740-0 | [Molecular Formula]
C4H8N2 | [MDL Number]
MFCD00001954 | [Molecular Weight]
84.12 | [MOL File]
693-05-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21:Harmful by inhalation and in contact with skin .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
TZ4910000
| [HazardClass ]
IRRITANT | [HS Code ]
29269095 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR YELLOW LIQUID | [Uses]
(3-MethylaMinopropionitrile) Aminoproponitriles can be used as inhibitors of oxidase enzymes and as a reagent for aminomethylphosphine ligands or the synthesis of aminobenzothiazoles.
| [Synthesis]
Below 15 °C, 160.8 g (3.0 mol, 99% purity) of 2-acrylonitrile was slowly added dropwise to 345.1 g (3.0 mol, 27% concentration) of monomethylamine solution while maintaining stirring. Upon completion of the reaction, the ethanol generated was removed by distillation at atmospheric pressure. The product was subsequently collected by vacuum distillation to give 210.6 g of 3-methylaminopropionitrile in 83.5% yield. | [References]
[1] Kinetics and Catalysis, 2010, vol. 51, # 5, p. 653 - 656
[2] Journal of Heterocyclic Chemistry, 1997, vol. 34, # 1, p. 87 - 91
[3] Patent: CN106632280, 2017, A. Location in patent: Paragraph 0023; 0024; 0025
[4] Patent: CN108003141, 2018, A. Location in patent: Paragraph 0032; 0035
[5] Liebigs Annalen der Chemie, 1980, # 9, p. 1438 - 1447 |
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