| Identification | Back Directory | [Name]
COBRATOXIN | [CAS]
69344-74-7 | [Synonyms]
COBRATOXIN
NEUROTOXIN 3
NEUROTOXIN III
ALPHA-COBRATOXIN
ALPHA-COBROTOXIN
alpha Toxin, naja
LONG NEUROTOXIN 1
Cobra alpha toxin
Cobra toxin alpha
Toxin alpha, cobra
MONOCELLATE COBRATOXIN
NAJA NAJA KAOUTHIA TOXIN
Snake toxin from Naja naja kaouthia
alpha-Cobratoxin (naja naja siamensis)
a-Cobratoxin from Naja naja kaouthia
α-Cobratoxin from Naja naja atra (Formosan Cobra) | [MDL Number]
MFCD00166511 |
| Safety Data | Back Directory | [WGK Germany ]
3 | [RTECS ]
GG4220000 | [Toxicity]
A small basic protein (Mr57000). It contains 62
amino acids in a single chain, cross-linked by four disulfide
bonds. The toxin comprises 10% of the venom by weight. It is
a neurotoxin that is secreted by glands of the cobra snake and
injected into its prey via immobile, grooved fangs. Cobratoxin
may be radiolabeled and used as a specific radioligand in binding
studies performed on acetylcholine receptors. Cobratoxin is absorbed from the subcutaneous tissues and is distributed
throughout the body. After intoxication, high concentrations
are found at the motor endplates of neuromuscular junctions,
where it irreversibly binds to acetylcholine receptors. The primary
action is similar to that of curare, but the binding process
is slower. |
| Hazard Information | Back Directory | [Description]
Cobratoxin is the protein isolated from the venom of the cobra, Naja atra. The protein contains 83 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids. |
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