| Identification | More | [Name]
2-Fluoroadenine | [CAS]
700-49-2 | [Synonyms]
2-FLUORO-6-AMINOPURINE
2-FLUORO-7(9)H-PURIN-6-YLAMINE
2-FLUOROADENINE
6-AMINO-2-FLUOROPURINE
BUTTPARK 25\01-01
2-fad
2-fluoro-1h-purin-6-amin
2-fluoro-1h-purin-6-amine
2-fluoro-adenin
6-amino-2-fluoro-purin
nsc27364
2-Fluoro-9H-purin-6-amine
6-Amino-2-fluoro-1H-purine | [EINECS(EC#)]
624-159-6 | [Molecular Formula]
C5H4FN5 | [MDL Number]
MFCD01632749 | [Molecular Weight]
153.12 | [MOL File]
700-49-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
>350 °C(lit.)
| [Boiling point ]
239.6±50.0 °C(Predicted) | [density ]
2.05±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
6.84±0.20(Predicted) | [color ]
White to Light Yellow | [Usage]
A purine nucleoside phosphorylase gene therapy for human malignancy. | [InChI]
InChI=1S/C5H4FN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11) | [InChIKey]
WKMPTBDYDNUJLF-UHFFFAOYSA-N | [SMILES]
N1C2C(=NC(F)=NC=2N)NC=1 | [CAS DataBase Reference]
700-49-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
AU6264700
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT, IRRITANT-HARMFUL | [HS Code ]
29335990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy. It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. It is also cytotoxic to CEM human leukemia cells with an IC50 value of 0.15 μM. | [Chemical Properties]
white to light yellow crystal powder | [Uses]
A purine nucleoside phosphorylase gene therapy for human malignancy. | [Definition]
ChEBI: An organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|