| Identification | More | [Name]
Cefaclor monohydrate | [CAS]
70356-03-5 | [Synonyms]
CEFACLOR HYDRATE
CEFACLOR MONOHYDRATE
lilly99638hydrate
monohydrate,(6r-(6-alpha,7-beta(r*)))-ino)-3-chloro-8-oxo
panoralhydrate
3-chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid monohydrate
Ceclor
Cefactor
(6R,7R)-7-[(2-Amino-2-phenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monohydrate
Distaclor
Keflor
Raniclor
CEFACLOR,MONOHYDRATE,USP
8-(2-AMINO-2-PHENYLACETYL)AMINO-4-CHLORO-7-OXO-2-THIA-6-AZABICYCLO[4,2,0]OCT-4-ENE-5-CARBOXYLICACID
[6R-[6α，7β(R^<*>^)]]-7-[(Aminophenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2.ene-2-carboxylic acidmonohydrate
Alfatil
Panacef
8-(2-Amino-2-phenylacetyl)amino-4-chloro-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid monohydrate
(7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt
Muco-panoral | [EINECS(EC#)]
258-909-5 | [Molecular Formula]
C15H16ClN3O5S | [MDL Number]
MFCD00071999 | [Molecular Weight]
385.82 | [MOL File]
70356-03-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
>180°C (dec.) | [storage temp. ]
-20?C Freezer | [solubility ]
Slightly soluble in water, practically insoluble in methanol and in methylene chloride. | [form ]
neat | [color ]
White to Light Beige | [Usage]
Second-generation cephalosporin antibiotic. Antibacterial | [InChI]
InChI=1/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/s3 | [Contact allergens]
Cefaclor is a semisynthetic cephalosporin antibiotic,
related to cefalexin, and a frequent inducer of serum
sickness-like reactions. | [InChIKey]
WKJGTOYAEQDNIA-UZPHMIKQNA-N | [SMILES]
O=C1[C@@H](NC(=O)[C@@H](C2C=CC=CC=2)N)[C@@]2([H])SCC(Cl)=C(C(=O)O)N12.O |&1:2,6,14,r| | [CAS DataBase Reference]
70356-03-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Antibacterial;Bacterial transpeptidase inhibitor | [Uses]
Second-generation cephalosporin antibiotic. Antibacterial | [Description]
Cefaclor was found by Eli Lilly & Co. in 1976 in the course of studies on the improvement of synthetic procedures for cephalexin. The intermediates with chlorine at the 3 position of the cephem nucleus have excellent antibacterial activity. Cefaclor was selected from among the various derivatives that differed at the 7 position because of its strong activity and high bioavailability following oral administration. | [Brand name]
Ceclor (Lilly); Raniclor (Ranbaxy). | [storage]
Store at -20°C |
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