| Identification | Back Directory | [Name]
Sativanone | [CAS]
70561-31-8 | [Synonyms]
Sativanone 4H-1-Benzopyran-4-one, 3-(2,4-dimethoxyphenyl)-2,3-dihydro-7-hydroxy-, (3R)- | [Molecular Formula]
C17H16O5 | [MOL File]
70561-31-8.mol | [Molecular Weight]
300.31 |
| Chemical Properties | Back Directory | [Boiling point ]
520.6±50.0 °C(Predicted) | [density ]
1.281±0.06 g/cm3(Predicted) | [pka]
7.68±0.40(Predicted) | [InChI]
InChI=1S/C17H16O5/c1-20-11-4-6-12(15(8-11)21-2)14-9-22-16-7-10(18)3-5-13(16)17(14)19/h3-8,14,18H,9H2,1-2H3/t14-/m0/s1 | [InChIKey]
JOVYBWHPTQRVNZ-AWEZNQCLSA-N | [SMILES]
C1OC2=CC(O)=CC=C2C(=O)[C@@H]1C1=CC=C(OC)C=C1OC |
| Hazard Information | Back Directory | [Uses]
Sativanone is a compound that can be isolated from Dalbergia tonkinensis. Sativanone is a potent α-glucosidase inhibitor, with an EC50 of 0.357 mg/mL for rat α-glucosidase. Sativanone has antibacterial activity against Ralstonia solanacearum. Sativanone also has anti-senescent and antioxidant effects[1]. | [Definition]
ChEBI: Sativanone is a member of flavonoids and an ether. | [References]
[1] Nguyen VB, et al. New Records of Potent In-Vitro Antidiabetic Properties of Dalbergia tonkinensis Heartwood and the Bioactivity-Guided Isolation of Active Compounds. Molecules. 2018 Jun 29;23(7):1589. DOI:10.3390/molecules23071589 |
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