| Identification | More | [Name]
3,3-Dimethylbutyryl chloride | [CAS]
7065-46-5 | [Synonyms]
3,3-DIMETHYLBUTANOYL CHLORIDE
3,3-DIMETHYLBUTYRYL CHLORIDE
3,3-DIMETHYL-N-BUTYRYL CHLORIDE
AKOS BBS-00003928
TBAC
T-BUTYLACETYL CHLORIDE
TERT-BUTYLACETYL CHLORIDE
3,3-dimethyl-butanoylchlorid
Butanoyl chloride, 3,3-dimethyl-
butylacetylchloride
Chloroacetoacetamides
tert-Butylacetyl chloride, 98+%
3,3-Dimethylbutyric acid chloride
3,3-Dimethylbutanoic acid chloride | [EINECS(EC#)]
230-356-4 | [Molecular Formula]
C6H11ClO | [MDL Number]
MFCD00000737 | [Molecular Weight]
134.6 | [MOL File]
7065-46-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to slightly yellow liquid | [Boiling point ]
127-129 °C (lit.) | [density ]
0.969 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.421(lit.)
| [Fp ]
70 °F
| [storage temp. ]
0-6°C | [form ]
Liquid | [color ]
Clear colorless to slightly yellow | [Water Solubility ]
Reacts with water. | [Sensitive ]
Moisture Sensitive | [BRN ]
1740421 | [InChI]
InChI=1S/C6H11ClO/c1-6(2,3)4-5(7)8/h4H2,1-3H3 | [InChIKey]
BUTKIHRNYUEGKB-UHFFFAOYSA-N | [SMILES]
C(Cl)(=O)CC(C)(C)C | [CAS DataBase Reference]
7065-46-5(CAS DataBase Reference) | [NIST Chemistry Reference]
tert-Butyl acetyl chloride(7065-46-5) | [EPA Substance Registry System]
7065-46-5(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS02,GHS05 | [Signal word ]
Danger | [Hazard statements ]
H225-H315-H318 | [Precautionary statements ]
P210-P280-P305+P351+P338 | [Hazard Codes ]
C | [Risk Statements ]
R10:Flammable.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2924 3/PG 2
| [WGK Germany ]
3
| [F ]
9-13-21 | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29159000 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Eye Dam. 1
Flam. Liq. 2
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to slightly yellow liquid | [Uses]
3,3-Dimethylbutyryl Chloride is a useful compound in organic synthesis. | [Application]
3,3-Dimethylbutyryl chloride is a very important acylation reagent, mainly used as a pharmaceutical intermediate.
| [Synthesis]
Add 3,3-dimethylbutyric acid into the reactor, stir, add phosphorus trichloride, raise the temperature to the reaction temperature for reaction, cool to room temperature after the reaction, and stand for stratification; separate after standing for stratification The phosphorous acid in the lower layer is used as a by-product, and the crude acid chloride in the upper layer is collected under reduced pressure distillation at an absolute pressure of 20KPa to collect a fraction at 79-81°C to obtain 3,3-dimethylbutyryl chloride product.
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| Company Name: |
Qi-Chem Co., Ltd. Gold
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| Telephone: |
0411-88165951 13601035838 |
| Website: |
http://www.qi-chem.com/ |
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J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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