| Identification | Back Directory | [Name]
methyl N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate | [CAS]
7134-19-2 | [Synonyms]
methyl N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate
Benzenesulfinimidic acid, N-[(4-chlorophenyl)sulfonyl]-4-nitro-, methyl ester | [Molecular Formula]
C13H11ClN2O5S2 | [MDL Number]
MFCD03040968 | [MOL File]
7134-19-2.mol | [Molecular Weight]
374.82 |
| Hazard Information | Back Directory | [Uses]
CCG-4986 is an RGS protein inhibitor. CCG-4986 inhibits protein activity by covalently modifying the Cys-132 site of RGS4. CCG-4986 can be used to study diseases related to dysregulated G protein-coupled receptor (GPCR) signaling, such as Parkinson's disease and opioid addiction[1]. | [IC 50]
RGS4 | [References]
[1] Kimple AJ, et al. The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face. Biochim Biophys Acta. 2007 Sep;1774(9):1213-20. DOI:10.1016/j.bbapap.2007.06.002 |
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