ChemicalBook--->CAS DataBase List--->7138-34-3

7138-34-3

7138-34-3 Structure

7138-34-3 Structure
IdentificationMore
[Name]

4-Chloromandelic acid
[CAS]

7138-34-3
[Synonyms]

2-(4-chlorophenyl)-2-hydroxyacetic acid
4-CHLORO-ALPHA-HYDROXYPHENYLACETIC ACID
4-CHLORO-DL-MANDELIC ACID
4-CHLOROMANDELIC ACID
(4-CHLOROPHENYL)(HYDROXY)ACETIC ACID
D/L-4'-CHLOROMANDELIC ACID
D,L-HYDROXY-(4-CHLOROPHENYL)ACETIC ACID
DL-P-CHLORO MANDELIC ACID
P-CHLORO-DL-MANDELIC ACID
P-CHLOROMANDELIC ACID
TIMTEC-BB SBB008325
Chloromandelicacid
4-CHLORO-DL-MANDELIC ACID 98+%
4-Chloromandelic acid
(±)-(p-Chlorophenyl)glycolic acid
DL-(p-Chlorophenyl)glycolic acid
rac-(R*)-4-Chlorobenzeneglycolic acid
[EINECS(EC#)]

207-764-6
[Molecular Formula]

C8H7ClO3
[MDL Number]

MFCD00042724
[Molecular Weight]

186.59
[MOL File]

7138-34-3.mol
Chemical PropertiesBack Directory
[Melting point ]

114-118 °C
[InChI]

InChI=1S/C8H7ClO3/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,7,10H,(H,11,12)
[InChIKey]

BWSFWXSSALIZAU-UHFFFAOYSA-N
[SMILES]

C(O)(=O)C(C1=CC=C(Cl)C=C1)O
[CAS DataBase Reference]

7138-34-3(CAS DataBase Reference)
[EPA Substance Registry System]

7138-34-3(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[Hazard Codes ]

Xn
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed.
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

4-?Chloromandelic acid has been used as a catalyst for Michael Addition of 2-?(1-?Ethylpropoxy)?acetaldehyde to N-?[(1Z)?-?2-?Nitroethenyl]?acetamide. As well, it has been used as a nucleation inhibitor for dutch resolution for diastereomers of racemic 3-?methoxyphenylethylamine with chiral mandelic acid.
[Application]

4-chloro mandelic acid, has R type and S type two kinds of enantiomorph configurations, is all widely used in multiple fields such as medicine production, asymmetric synthesis, optical resolution.
[Hazard]

4-Chloromandelic acid causes skin irritation and serious eye irritation.
[Chemical Reactivity]

4-chloromandelic acid and the chiral resolution agent (R)-(+)-1-(1-naphthyl)ethylamine react in a suitable alcohol solvent to generate (R)-(+)-1-(1-naphthyl)ethylamine salt of the 4-chloromandelic acid, by using different solubilities of an enantiomer salt, crystallizing and suction filtration are performed to obtain the (R)-(+)-1-(1-naphthyl)ethylamine salt of the (R)-(-)-4-chloromandelic acid.
Spectrum DetailBack Directory
[Spectrum Detail]

4-Chloromandelic acid(7138-34-3)MS
4-Chloromandelic acid(7138-34-3)1HNMR
4-Chloromandelic acid(7138-34-3)IR1
Well-known Reagent Company Product InformationBack Directory
[TCI AMERICA]

4-Chloro-DL-mandelic Acid,>98.0%(T)(7138-34-3)
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