| Identification | More | [Name]
Dihydralazine sulphate | [CAS]
7327-87-9 | [Synonyms]
DIHYDRALAZINE SULFATE
DIHYDRALAZINE SULFATE HYDRATE
DIHYDRALAZINE SULPHATE
1,4-dihydrazinophthalazinesulfate
1,4-dihydrazino-phthalazinsulfate(1:1)
depressan
sulfatededihydralazine
1,4-Dihydrazinophthalazine·sulfuric acid | [EINECS(EC#)]
230-808-0 | [Molecular Formula]
C8H12N6O4S | [MDL Number]
MFCD00035271 | [Molecular Weight]
288.28 | [MOL File]
7327-87-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
>235°C (subl.) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO: soluble1mg/mL | [form ]
powder | [color ]
Off-White to Pale Yellow | [InChI]
InChI=1S/C8H10N6.H2O4S/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7;1-5(2,3)4/h1-4H,9-10H2,(H,11,13)(H,12,14);(H2,1,2,3,4) | [InChIKey]
BWHAMWGGORIDBK-UHFFFAOYSA-N | [SMILES]
N(=C1/NN/C(=N\N)/C2C=CC=CC/1=2)/N.S(O)(O)(=O)=O | [CAS DataBase Reference]
7327-87-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Dihydralazine sulfate is a vasodilator and an antihypertensive agent. It relaxes arterial smooth muscle by inhibiting the accumulation of intracellular free calcium. By relaxing vascular smooth muscle, vasodilators act to decrease peripheral resistance.? | [Chemical Properties]
Off-White Solid | [Uses]
Dihydralazine sulphate is an antihypertensive agent of the hydrazine class used during pregnancies in dialysis patients with familial mediterranean fever and cystinosis under hemodialysis.
| [Application]
Dihydralazine sulphate (Nepresol) is a dihydralazine-1,4-phthalazine derivative and used as an antihypertensive drug. | [Mode of action]
cell membrane | interferes |
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