| Identification | More | [Name]
N-(Carbamoylmethyl)taurine | [CAS]
7365-82-4 | [Synonyms]
2-[(2-AMINO-2-OXOETHYL)AMINO]ETHANESULFONIC ACID
2-(CARBAMOYLMETHYLAMINO)ETHANESULFONIC ACID
ACES
ACES BUFFER
LABOTEST-BB LT00012617
N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID
N-(2-ACETAMIDO)-2-AMINOETHANESULPHONIC ACID
N-(CARBAMOYLMETHYL)-2-AMINOETHANESULFONIC ACID
N-(CARBAMOYLMETHYL)TAURINE
TIMTEC-BB SBB006711
2-[(2-amino-2-oxoethyl)amino]-ethanesulfonicaci
N-(2-Acetamido)-2-aminoethanesulfonic acid
N-(Carbamoylmethyl)taurine
ACES, BIOTECHNOLOGY PERFORMANCE CERTIFIE D
ACES SIGMAULTRA
ACES, 99% (N-(2-ACETAMIDO)-2-AMINOETHANE-SULFONIC ACID)
N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID BUFFER SUBSTANCE ACES
ACES, BIOGRADE
ACES 2-[(2-AMINO-2-OXYETHYL) AMINO] ETHANE SULFONIC ACID N-(2-ACETAMIDO)-2-AMINOETHANE SULFONIC ACID) HIGH PURITY GRADE
N-(2-ACETAMIDO0-2-AMINOETHANESULFONIC ACID
AcesN-(2-Acetamido)-2-AminoethanesulfonicAcid | [EINECS(EC#)]
230-908-4 | [Molecular Formula]
C4H10N2O4S | [MDL Number]
MFCD00008030 | [Molecular Weight]
182.2 | [MOL File]
7365-82-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystals | [Melting point ]
>220 °C (dec.)(lit.)
| [Boiling point ]
404.49℃ | [density ]
1.484±0.06 g/cm3(Predicted) | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
Store at RT. | [solubility ]
H2O: 0.1 M at 20 °C, clear, colorless
| [form ]
Crystals | [color ]
White | [PH]
2.5-4.5 (25℃, 0.1M in H2O) | [PH Range]
6.1 - 7.5 | [pka]
6.8(at 25℃) | [biological source]
synthetic | [Water Solubility ]
soluble | [λmax]
λ: 260 nm Amax: 0.008
λ: 280 nm Amax: 0.005 | [Merck ]
14,36 | [BRN ]
2253770 | [Major Application]
diagnostic assay manufacturing | [InChI]
1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10) | [InChIKey]
DBXNUXBLKRLWFA-UHFFFAOYSA-N | [SMILES]
NC(=O)CNCCS(O)(=O)=O | [LogP]
-4.49 at 25℃ | [CAS DataBase Reference]
7365-82-4(CAS DataBase Reference) | [EPA Substance Registry System]
7365-82-4(EPA Substance) | [Absorption]
≤0.05 at 260 in H2O at 0.1M
≤0.05 at 280 in H2O at 0.1M |
| Hazard Information | Back Directory | [Description]
ACES is a zwitterionic buffering agent used in biochemistry and molecular biology that was first selected and described by Good et al. It is a paraacetamide buffer suitable for environments with a pH of 6.1 - 7.5. ACES can be used as a buffer component in cell culture media for use in agarose and polyacrylamide electrophoresis and in isoelectric focusing of proteins. It forms complexes with most common metals, and the formation constant should be taken into account when using such buffers in solutions containing metal ions.
| [Chemical Properties]
N-(Carbamoylmethyl)taurine is white crystals
| [Uses]
Buffer for biological systems. | [Uses]
N-(Carbamoylmethyl)taurine can be used to study biological buffers and zwitterionic compounds. ACES has been used in a study to determine the levels of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis.
| [Definition]
ChEBI: N-(2-acetamido)-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate. | [Preparation]
In the presence of the reaction solvent tetrahydrofuran, add nitrogen-containing reagent ammonia into the reactor to react with the raw material, wherein the molar ratio of ammonia to theraw material is 1:1. The reaction temperature is 60°C, the reaction pressure is 1 MPa (gauge pressure), and the reaction time is 8 hours. After the reaction is completed, it is acidified to generate ACES. Then spin off the solvent tetrahydrofuran, add ethyl acetate, wash twice with water, dry with anhydrous sodium sulfate, and spin off the ethyl acetate to obtain the crude ACES. Purification stepIn the reactor, the purified solvent tetrahydrofuran was added to dissolve the crude ACES, recrystallized at low temperature, the insoluble matter was removed by suction, and the filtrate was rotary evaporated to remove tetrahydrofuran to obtain refined ACES.
 | [storage]
Store at -20°C | [Purification Methods]
Recrystallise ACES from hot aqueous EtOH. [Perrin & Dempsey Buffers for pH and Metal Ion Control Chapman & Hall, London 1974, Beilstein 4 III 1707.] |
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