| Identification | More | [Name]
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid | [CAS]
73731-37-0 | [Synonyms]
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
FMOC-L-THREONINE
FMOC-L-THREONINE MONOHYDRATE
FMOC-L-THR-OH
FMOC-L-THR-OH H2O
FMOC-THREONINE
FMOC-THR-OH
FMOC-THR-OH H2O
FMOC-THR-OH MONOHYDRATE
N-(9-FLUORENYLMETHOXYCARBONYL)-L-THREONINE
N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-THREONINE MONOHYDRATE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-THREONINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-THREONINE
N-ALPHA-FMOC-L-THREONINE
N-FMOC-L-THREONINE
N-FMOC-L-THREONINE MONOHYDRATE
N-[(9H-Fluoren-9ylmethoxy)carbonyl]-L-threonine
Fmoc-Thr-OH•
FMOC-THR
FMOC-L-THREONINE extrapure | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C19H19NO5 | [MDL Number]
MFCD00077072 | [Molecular Weight]
341.36 | [MOL File]
73731-37-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
115°C (dec.) | [alpha ]
-16 º (c=1%, DMF) | [Boiling point ]
596.5±50.0 °C(Predicted) | [density ]
1.327±0.06 g/cm3(Predicted) | [refractive index ]
-15.5 ° (C=1, DMF) | [storage temp. ]
2-8°C
| [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
3.49±0.10(Predicted) | [color ]
White to Almost white | [Optical Rotation]
[α]20/D 16±1°, c = 1% in DMF | [Detection Methods]
T,NMR,Rotation | [BRN ]
4300093 | [Major Application]
peptide synthesis | [InChI]
1S/C19H19NO5.H2O/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16;/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23);1H2/t11-,17+;/m1./s1 | [InChIKey]
CGNQPFAECJFQNV-NRNQBQMASA-N | [SMILES]
O.C[C@@H](O)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O | [CAS DataBase Reference]
73731-37-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29242990 | [Storage Class]
13 - Non Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
N-Fmoc-L-threonine is an N-Fmoc-protected form of L-Threonine (T405500). L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin). | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis | [References]
[1] European Journal of Organic Chemistry, 2011, # 20-21, p. 3685 - 3689
[2] Tetrahedron, 2012, vol. 68, # 2, p. 697 - 704
[3] ChemBioChem, 2018, vol. 19, # 11, p. 1142 - 1146
[4] Tetrahedron Letters, 1993, vol. 34, # 24, p. 3837 - 3840
[5] Australian Journal of Chemistry, 2011, vol. 64, # 6, p. 723 - 731 |
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