| Identification | More | [Name]
Clofentezine | [CAS]
74115-24-5 | [Synonyms]
3,6-BIS(2-CHLOROPHENYL)-1,2,4,5-TETRAZINE
ACARISTOP(R)
APOLLO
APOLLO(R)
CLOFENTEZIN
CLOFENTEZINE
4,5-tetrazine,3,6-bis(2-chlorophenyl)-2
acaristop
apollo50w
apolo
appollo50sc
bisclofentazin
bisclofentazine
nc21314
Apollo? Apollo SC
Bis(2-chlorophenyl)-1,2,4,5-tetrazine
Panatac
3,6-bis(o-chlorophenyl)-1,2,4,5-tetrazine
Apollo(FBC)
CLOFENTEZIN PESTANAL (3,6-BIS(2-CHLOROP | [EINECS(EC#)]
277-728-2 | [Molecular Formula]
C14H8Cl2N4 | [MDL Number]
MFCD00143998 | [Molecular Weight]
303.15 | [MOL File]
74115-24-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Magenta crystalline solid | [Melting point ]
182-185 °C(lit.) | [Boiling point ]
457.37°C (rough estimate) | [density ]
1.3727 (rough estimate) | [refractive index ]
1.6300 (estimate) | [storage temp. ]
0-6°C | [solubility ]
Chloroform: Slightly Soluble | [form ]
neat | [pka]
-1.68±0.31(Predicted) | [color ]
Light yellow to yellow | [Water Solubility ]
2.522ug/L(temperature not stated) | [Merck ]
13,2398 | [BRN ]
7137128 | [Henry's Law Constant]
2.5×104 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [Major Application]
agriculture
environmental | [InChI]
1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H | [InChIKey]
UXADOQPNKNTIHB-UHFFFAOYSA-N | [SMILES]
Clc1ccccc1-c2nnc(nn2)-c3ccccc3Cl | [LogP]
3.100 | [CAS DataBase Reference]
74115-24-5(CAS DataBase Reference) | [EPA Substance Registry System]
74115-24-5(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3
| [RTECS ]
XF6860000
| [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Chronic 1 | [Toxicity]
LD50 in rats, mice (mg/kg): >3200 orally; LC50 (96 hr) in rainbow trout: 100 mg/l (Bryan) |
| Hazard Information | Back Directory | [Potential Exposure]
Tetrazine miticide used on a wide variety of cropsfruit, cereals, rangeland, ornamentals, etc. An EPA Restricted Use Pesticide (RUP). | [First aid]
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions) if breathing has stopped, and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit | [Shipping]
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required | [Incompatibilities]
Oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); strong acids. Decomposes above 185°C | [Description]
Clofentazine is a selective insecticide used to control mites. It has a low aqueous solubility and is not volatile. It is moderately persistent in soil systems but tends not to be in aquatic systems. Based on its physico-chemical properties it is not expected to leach to groundwater. Clofentazine is highly toxic to birds and fish and moderately toxic to aquatic invertebrates, honeybees and earthworms. It has a low mammalian toxicity. | [Chemical Properties]
Magenta crystalline solid | [Waste Disposal]
Do not discharge into drains or sewers. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. | [Uses]
Clofentezine is a mite growth regular and an tetrazine based acaricide. Clofentezine is used in agriculture for the protection of ornamentals, food and non-food crops in the field. | [Uses]
Pesticide. | [Definition]
ChEBI: A tetrazine that is 1,2,4,5-tetrazine in which both of the hydrogens have been replaced by o-chlorophenyl groups. | [Production Methods]
Clofentezine is produced commercially through a multi-step chemical synthesis involving chlorination, oxidation, and condensation reactions. The process typically begins with the chlorination of an aromatic precursor to introduce chlorine atoms at specific positions. This is followed by an oxidation step to prepare the intermediate compounds necessary for the final condensation reaction. The condensation step involves combining these intermediates under controlled conditions to form clofentezine. | [Agricultural Uses]
Miticide: A U.S. EPA restricted Use Pesticide (RUP). Used
on a wide variety of crops – fruit, cereals, rangeland, ornamentals, etc | [Trade name]
APOLLO®; OVATION® | [Mechanism of action]
Specific with contact action and long residual activity. Mite growth inhibitor affecting CHS1. | [storage]
Store at -20°C | [Pesticide Type]
Acaricide; Insecticide |
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