| Identification | Back Directory | [Name]
2H-Naphtho[1,8-bc]furan-2-one, 6,7,8,8a-tetrahydro- | [CAS]
74145-12-3 | [Synonyms]
Palonosetron Impurity 53
6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one
2H-?Naphtho[1,?8-?bc]?furan-?2-?one, 6,?7,?8,?8a-?tetrahydro- | [Molecular Formula]
C11H10O2 | [MOL File]
74145-12-3.mol | [Molecular Weight]
174.2 |
| Chemical Properties | Back Directory | [Boiling point ]
349.8±41.0 °C(Predicted) | [density ]
1.264±0.06 g/cm3(Predicted) | [storage temp. ]
Room Temperature | [solubility ]
Dichloromethane; Methanol; Ethyl Acetate; | [form ]
Solid | [color ]
Pale Yellow |
| Hazard Information | Back Directory | [Uses]
6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one is an intermediate used in the synthesis of N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide (A795305), which is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic. |
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