| Identification | Back Directory | [Name]
(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) | [CAS]
75217-63-9 | [Synonyms]
GLUCAGON, HUMAN
GLUCAGON PEPTIDE
GLUCAGON, HUMAN/RAT
GLUCAGON (1-29), HUMAN
glucagon, Met-sulfoxide(27)-
HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
GLUCAGON HUMAN, BOVINE, PORCINE
GLUCAGON (1-29), BOVINE, HUMAN, PORCINE
GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)
Glucagon (swine), 27-(L-methionine S-oxide)-
(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)
ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR: AQDFVQWLMNT
(MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) USP/EP/BP
(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt
HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR
H-HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET(O)-ASN-THR-OH | [Molecular Formula]
C153H225N43O50S | [MDL Number]
MFCD08458617 | [MOL File]
75217-63-9.mol | [Molecular Weight]
3498.75 |
| Chemical Properties | Back Directory | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [Sequence]
His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-{Met(O)}-Asn-Thr |
| Hazard Information | Back Directory | [Uses]
(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1]. | [References]
[1] Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63. DOI:10.1055/s-0028-1092761 |
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