| Identification | Back Directory | [Name]
(+)-MK 801 MALEATE | [CAS]
77086-19-2 | [Synonyms]
()-MK-801
(-)-MK 801 MALEATE
(+)-MK 801 MALEATE
DIZOCILPINE MALEATE
(+)-MK-801 HYDROGEN MALEATE
(-)-MK 801 hydrogen maleate
5,10-Imino-5H-dibenzo[a,d]cycloheptene, 10,11-dihydro-5-methyl-,(5R,10S)-
(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-iminemaleate
(5R,10S)-(-)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5,10-IMINE MALEATE
(5R,10S)-(+)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]-CYCLOHEPTEN-5-10-IMINE, MALEATE
(5R,10S)-(-)-5-Methyl-10,11-dihydro-(5H)-dibenzo[a.d]cylcoheptene-5,10-iminemaleate
(5R,10S)-(+)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5,10-IMINE HYDROGEN MALEATE
(5s,10r)-(-)-5-methyl-10,11-dihydro-5h-dibenzo-[a,d]-cyclo-hepten-5,10-imine hydrogen maleate | [Molecular Formula]
C16H15N | [MDL Number]
MFCD00082466 | [MOL File]
77086-19-2.mol | [Molecular Weight]
221.3 |
| Chemical Properties | Back Directory | [Melting point ]
68.5-69.5° | [alpha ]
589 -160.8° (c = 0.032 g/2 ml ethanol) | [storage temp. ]
room temp | [solubility ]
DMSO: >20mg/mL | [form ]
solid | [color ]
white | [Optical Rotation]
[α]25/D 117.7°, c = 1 in methanol(lit.) | [InChI]
1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m0./s1 | [InChIKey]
QLTXKCWMEZIHBJ-FWHYOZOBSA-N | [SMILES]
[H]\C(=C(/[H])C(O)=O)C(O)=O.[H][C@@]12Cc3ccccc3[C@@](C)(N1)c4ccccc24 |
| Hazard Information | Back Directory | [Uses]
Biochemical probe for NMDA receptors. | [General Description]
(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801. | [Biological Activity]
Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ). | [Biochem/physiol Actions]
Less active enantiomer of (+)-MK-801 hydrogen maleate |
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