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77303-64-1

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77303-64-1 Structure

77303-64-1 Structure
IdentificationBack Directory
[Name]

Hydroxy-PEG4-CH2CO2Me
[CAS]

77303-64-1
[Synonyms]

HO-PEG4-CH2COOMe
Hydroxy-PEG4-CH2CO2Me
Hydroxy-PEG4-methyl acetate
3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
HO-PEG4-CH2COOMe/3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
[Molecular Formula]

C11H22O7
[MDL Number]

MFCD30828688
[MOL File]

77303-64-1.mol
[Molecular Weight]

266.29
Chemical PropertiesBack Directory
[Boiling point ]

120 °C(Press: 0.001 Torr)
[density ]

1.125±0.06 g/cm3(Predicted)
[form ]

Liquid
[pka]

14.36±0.10(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

Hydroxy-PEG4-CH2CO2Me(77303-64-1)1HNMR
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