ChemicalBook--->CAS DataBase List--->786-97-0

786-97-0

786-97-0 Structure

786-97-0 Structure
IdentificationBack Directory
[Name]

SU 10603
[CAS]

786-97-0
[Synonyms]

SU 10603
7-chloro-2-pyridin-3-yl-tetralin-1-one
7-Chloro-3,4-dihydro-2-(3-pyridyl)-1(2H)-naphthalenone
[Molecular Formula]

C15H12ClNO
[MDL Number]

MFCD00872822
[MOL File]

786-97-0.mol
[Molecular Weight]

257.71
Chemical PropertiesBack Directory
[Melting point ]

95-96 °C
[Boiling point ]

430.1±45.0 °C(Predicted)
[density ]

1.275±0.06 g/cm3(Predicted)
[pka]

4.60±0.12(Predicted)
Hazard InformationBack Directory
[Description]

SU 10603 is a 17-OH-steroid hydroxylase antagonist.
[Uses]

SU 10603 is a specific inhibitor of P45017α (P450c17; CYP17A1)[1].
[References]

[1] Hojo Y, et al. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):865-70. DOI:10.1073/pnas.2630225100
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