| Identification | Back Directory | [Name]
FIBRINOGEN GAMMA-CHAIN (397-411) | [CAS]
80755-86-8 | [Synonyms]
GQQHHLGGAKQAGDV
FIBRINOGEN RELATED PEPTIDE
Fibrinogen g-Chain (397-411)
FIBRINOGEN GAMMA-CHAIN (397-411)
906:PN:US20090175821 SEQID:1152 claimed protein
GLY-GLN-GLN-HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL
H-GLY-GLN-GLN-HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL-OH
L-Valine, glycyl-L-glutaminyl-L-glutaminyl-L-histidyl-L-histidyl-L-leucylglycylglycyl-L-alanyl-L-lysyl-L-glutaminyl-L-alanylglycyl-L-α-aspartyl- | [Molecular Formula]
C62H99N23O21 | [MDL Number]
MFCD00133316 | [MOL File]
80755-86-8.mol | [Molecular Weight]
1502.59 |
| Chemical Properties | Back Directory | [Boiling point ]
2141.2±65.0 °C(Predicted) | [density ]
1.360±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C
| [form ]
Solid | [pka]
3.20±0.10(Predicted) | [Sequence]
Gly-Gln-Gln-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val |
| Hazard Information | Back Directory | [Uses]
Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers[1][2]. | [References]
[1] Kloczewiak M, et al. Recognition site for the platelet receptor is present on the 15-residue carboxy-terminal fragment of the gamma chain of human fibrinogen and is not involved in the fibrin polymerization reaction. Thromb Res. 1983 Jan 15;29(2):249-55. DOI:10.1016/0049-3848(83)90147-0
[2] Kloczewiak M, et al. Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the gamma chain. Biochemistry. 1984 Apr 10;23(8):1767-74. DOI:10.1021/bi00303a028 |
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