| Identification | Back Directory | [Name]
L 741626 | [CAS]
81226-60-0 | [Synonyms]
3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL
receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit | [Molecular Formula]
C20H21ClN2O | [MDL Number]
MFCD00953632 | [MOL File]
81226-60-0.mol | [Molecular Weight]
340.852 |
| Chemical Properties | Back Directory | [Boiling point ]
548.8±50.0 °C(Predicted) | [density ]
1.311±0.06 g/cm3(Predicted) | [storage temp. ]
Room temp | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [pka]
13.87±0.20(Predicted) | [color ]
white to beige | [InChI]
1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 | [InChIKey]
LLBLNMUONVVVPG-UHFFFAOYSA-N | [SMILES]
OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4 |
| Hazard Information | Back Directory | [Hazard]
A poison. | [Uses]
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release. | [Uses]
L-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists. | [Definition]
ChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines. | [Biochem/physiol Actions]
L-741,626 is a selective dopamine (D2) receptor antagonist. | [storage]
Store at RT |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
|