ChemicalBook--->CAS DataBase List--->814-71-1

814-71-1

814-71-1 Structure

814-71-1 Structure
IdentificationMore
[Name]

Calcium thioglycolate
[CAS]

814-71-1
[Synonyms]

CALCIUM MERCAPTOACETATE TRIHYDRATE
CALCIUM THIOGLYCOLATE TRIHYDRATE
CALCIUM THIOGLYCOLLATE TRIHYDRATE
MERCAPTOACETIC ACID CALCIUM SALT TRIHYDRATE
THIOGLYCOLIC ACID CALCIUM SALT TRIHYDRATE
Aceticacid,mercapto-,calciumsalt(2:1)
Calciummercaptoacetate
Calciumthioglycollate
depil
ebacream
jully
mercapto-aceticacicalciumsalt(2:1)
mercaptoaceticacidcalciumderivative
vikor
calcium bis(mercaptoacetate)
CALCIUM THIOGLYCOLATE 3-HYDRATE
Acetic acid, mercapto-, calcium salt
Calcium thioglycolate
Calcium 2-sulfanylacetate
Bis(mercaptoacetic acid)calcium salt
[EINECS(EC#)]

212-402-5
[Molecular Formula]

C4H6CaO4S2
[MDL Number]

MFCD00150707
[Molecular Weight]

222.3
[MOL File]

814-71-1.mol
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C, sealed storage, away from moisture
[Appearance]

White to off-white Solid
[Water Solubility ]

soluble H2O [MER06]
[Merck ]

1711
[Cosmetics Ingredients Functions]

KERATOLYTIC
REDUCING
DEPILATORY
[InChI]

InChI=1S/2C2H4O2S.Ca/c2*3-2(4)1-5;/h2*5H,1H2,(H,3,4);/q;;+2/p-2
[InChIKey]

CNYFJCCVJNARLE-UHFFFAOYSA-L
[SMILES]

[Ca+2].C([O-])(=O)CS.C([O-])(=O)CS
[LogP]

0.089 (est)
[Uses]

calcium thioglycolate is used almost exclusively in depilatory creams and hair products. This is a calcium salt of thio-glycolic acid. It may cause skin irritation.
[CAS DataBase Reference]

814-71-1(CAS DataBase Reference)
[EPA Substance Registry System]

814-71-1(EPA Substance)
Hazard InformationBack Directory
[Chemical Properties]

white powder(s) or prismatic rod crystal(s); odorless or faint mercaptan odor; used in depilatories and in hair wave preparations [HAW93] [MER06]
[Description]

Calcium Thioglycolate is the calcium salt of thioglycolic acid. It is an active ingredient in some hair removal products. Calcium Thioglycolate opens the sulfur bridges in the Keratin structure of the hair, weakening the hair structure in the fibers and roots. This will break down disulfide bonds in Keratin and weaken the hair so that it is easily scrapped off from the hair follicle. It is an active ingredient in hair removal products such as depilatories. It is a fine-milled white powder with an alkaline pH value of 11-12. A depilatory containing calcium thioglycolate has a potent depilatory activity that leaves a soft, smooth, pleasant touch to the skin.
[Synthesis]

Sodium chloroacetate reacts with thiourea to give isothiourea-substituted acetic acid, which then reacts with calcium hydroxide to give the product:

HN=C(NH2)-S-CH2COOH + Ca(OH)2 → CaSC2H2O2-3H2O + H2NCN

Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[RIDADR ]

2811
[WGK Germany ]

1
[F ]

9-13-23
[TSCA ]

TSCA listed
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[Hazardous Substances Data]

814-71-1(Hazardous Substances Data)
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Calcium thioglycolate(814-71-1).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Calcium thioglycolate(814-71-1)IR1
Calcium thioglycolate(814-71-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

814-71-1(sigmaaldrich)
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