| Identification | More | [Name]
Inabenfide | [CAS]
82211-24-3 | [Synonyms]
INABENFIDE
SERITARD
4’-chloro-2’-(alpha-hydroxybenzyl)isonicotinanilide
cgr-811
n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamid
n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamide
4′-Chloro-2′-(α-hydroxybenzyl)isonicotinanilide
N-[4-Chloro-2-(hydroxy-phenylmethyl)phenyl]pyridine-4-carboxamide
N-[4-Chloro-2-(α-hydroxybenzyl)phenyl]isonicotinamide | [Molecular Formula]
C19H15ClN2O2 | [MDL Number]
MFCD00210319 | [Molecular Weight]
338.79 | [MOL File]
82211-24-3.mol |
| Questions And Answer | Back Directory | [Application]
Inabenfide (N-[4-chloro-2-(hydroxybenzyl)phenyl]pyridine-4-carboxamide) is a plant growth retardant that inhibits gibberellin synthesis in rice plants, exhibiting strong selective lodging resistance. After application, the number of grains per panicle decreases, but the grain maturity rate increases, leading to an increase in actual yield. Therefore, inabenfide is widely used in rice production. |
| Hazard Information | Back Directory | [Definition]
ChEBI:Inabenfide is a diarylmethane. | [Mechanism of action]
Gibberellin biosynthesis inhibitor causing a shortening of lower interlodes and upper leaf blades | [Synthesis]
Inabenfide is prepared as follows: isonicotinic acid is used as the starting material, and after chlorination by phthalic acid, it is reacted with 2-amino-5-chlorobenzophenone at a controlled temperature. After obtaining the intermediate ketone, the reduc | [Metabolic pathway]
In rats, inabenfide is mainly hydroxylated on the
phenyl ring which is not substituted by a chlorine atom
through epoxidation. Oxidation of the benzyl alcohol
gives benzophenone. The other hydroxylation is the
substitution of the chlorine with hydroxyl of the other phenyl ring possessing a chlorine atom. Also,
hydrolysis of the amide bond resulting in the
corresponding aniline and N-oxidation of the pyridine
nitrogen can be observed. | [Pesticide Type]
Herbicide; Plant Growth Regulator |
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