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82211-24-3

82211-24-3 Structure

82211-24-3 Structure
IdentificationMore
[Name]

Inabenfide
[CAS]

82211-24-3
[Synonyms]

INABENFIDE
SERITARD
4’-chloro-2’-(alpha-hydroxybenzyl)isonicotinanilide
cgr-811
n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamid
n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamide
4′-Chloro-2′-(α-hydroxybenzyl)isonicotinanilide
N-[4-Chloro-2-(hydroxy-phenylmethyl)phenyl]pyridine-4-carboxamide
N-[4-Chloro-2-(α-hydroxybenzyl)phenyl]isonicotinamide
[Molecular Formula]

C19H15ClN2O2
[MDL Number]

MFCD00210319
[Molecular Weight]

338.79
[MOL File]

82211-24-3.mol
Chemical PropertiesBack Directory
[Melting point ]

approximate 202℃ (dec.)
[Boiling point ]

454.6±45.0 °C(Predicted)
[density ]

1.2238 (rough estimate)
[refractive index ]

1.5400 (estimate)
[storage temp. ]

0-6°C
[form ]

neat
[pka]

10.77±0.70(Predicted)
[BRN ]

7042400
[CAS DataBase Reference]

82211-24-3(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

29333990
Hazard InformationBack Directory
[Definition]

ChEBI:Inabenfide is a diarylmethane.
[Metabolic pathway]

In rats, inabenfide is mainly hydroxylated on the phenyl ring which is not substituted by a chlorine atom through epoxidation. Oxidation of the benzyl alcohol gives benzophenone. The other hydroxylation is the substitution of the chlorine with hydroxyl of the other phenyl ring possessing a chlorine atom. Also, hydrolysis of the amide bond resulting in the corresponding aniline and N-oxidation of the pyridine nitrogen can be observed.
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