ChemicalBook--->CAS DataBase List--->82219-78-1

82219-78-1

82219-78-1 Structure

82219-78-1 Structure
IdentificationMore
[Name]

Cefuzonam
[CAS]

82219-78-1
[Synonyms]

1-[[(6r,7r)-7-[[(2z)-(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-imidazo[1,2-b]pyridazinium hydroxide inner salt
(6r,7s)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CEFUZONAM
Cefuzonam sodium
cefuzoname
(6R,7S)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
[6R-[(6α,7β(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxy-imino)acetyl]amino]-8-oxo-3-[(1,2,3-thiadiazol-5-yhhio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cosmosin
LJC-10305
CL-251931
CZON
L-105【Cephem antibiotic】
[Molecular Formula]

C16H15N7O5S4
[MDL Number]

MFCD00864878
[Molecular Weight]

513.59
[MOL File]

82219-78-1.mol
Chemical PropertiesBack Directory
[density ]

1.97±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

2+-.0.50(Predicted)
[CAS DataBase Reference]

82219-78-1(CAS DataBase Reference)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Magnesium sulfate-->Triethylamine-->Sodium bicarbonate-->Phosphorus pentachloride-->Activated carbon,decolor
Hazard InformationBack Directory
[Description]

Cefuzonam is an injectable cephalosporin reported to be active against a large percentage of Gram-negative bacteria and some Gram-positive bacteria, including those resistant to other third-generation cephdosporins.
[Originator]

Lederle (USA)
[Uses]

Cefuzonam is used for sepsis, acute bronchitis, tonsillitis, secondary infections of traumatic and surgical wounds, pharyngitis, arthritis, etc. caused by susceptible bacteria such as Haemophilus influenzae, Proteus spp., and Escherichia coli.
[Definition]

ChEBI: A second generation cephalosporin antibiotic.
[Brand name]

Cosmosin
Safety DataBack Directory
[Toxicity]

LD50 in female, male mice, female, male rats (mg/kg): 4117, >4800, 4281, 4222 i.v.; 6424, 6783, >8000, >8000 i.p.; all >10000 orally (Takita)
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