| Identification | More | [Name]
Triacetonamine | [CAS]
826-36-8 | [Synonyms]
2,2,6,6-TETRAMETHYL-4-PIPERIDINONE
2,2,6,6-TETRAMETHYL-4-PIPERIDONE
2,2,6,6-TETRAMETHYL-PIPERIDIN-4-ONE
2,2,6,6-TETRAMETHYLTETRAHYDRO-4(1H)-PYRIDINONE
LABOTEST-BB LT00159409
TAA
TETRAMETHYLPIPERIDINONE
TRIACETONAMINE
TRIACETONEAMINE
2,2,6,6-Tetramethyl-4-oxopiperidine
2,2,6,6-tetramethyl-4-piperidinon
2,2,6,6-tetramethyl-4-piperidon
2,2,6,6-Tetramethylpiperidinone
2,2,6,6-Tetramethylpiperidone
4-Oxo-2,2,6,6-tetramethylpiperidine
4-Piperidinone,2,2,6,6-tetramethyl-
4-Piperidone, 2,2,6,6-tetramethyl-
4-Piperidone,2,2,6,6-tetramethyl-
Ikh 196
IKh196 | [EINECS(EC#)]
212-554-2 | [Molecular Formula]
C9H15NO3 | [MDL Number]
MFCD00005975 | [Molecular Weight]
185.22 | [MOL File]
826-36-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xn | [Risk Statements ]
R34:Causes burns.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
2 | [RTECS ]
TO0127900 | [HS Code ]
29333990 |
| Questions And Answer | Back Directory | [Triacetone amine]
Triacetonamine has anti-arrhythmic and anti-myocardial ischemia effect.
Take Triacetonamine as raw materials, ethanol as the solvent, perform hydrogenation reaction in the presence of catalyst (normal pressure or 3~4MPa) and obtain raw material of histamine-type light stabilizer 2,2,6,6-tetramethyl-4-piperidinol.
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| [Chemical Properties]
It appears as white or light yellow powder with the melting point being 43 ℃ and boiling point being 205 ℃. It is soluble in acetone, alcohol, ether and water.
The above information is edited by the chemicalbook of Dai Xiongfeng.
| [Uses]
The product is the intermediate and pharmaceutical intermediate of histamine light stabilizer. Itself also has light-stabilizing effect. It has important application in pharmaceuticals.
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| Hazard Information | Back Directory | [Definition]
ChEBI: Triacetonamine is a member of piperidones. | [Synthesis Reference(s)]
Synthesis, p. 735, 1976 DOI: 10.1055/s-1976-24178 | [in vivo]
Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2]. | Animal Model: | Rats (half male and female, 6-8 weeks old, 200?±?10 g)[2] | | Dosage: | 200 mg, 300 mg, 400 mg/Kg | | Administration: | Gavage; daily; 2 days | | Result: | Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.
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