| Identification | More | [Name]
2,6-DIFLUORO-3-NITROBENZOIC ACID | [CAS]
83141-10-0 | [Synonyms]
2,6-DIFLUORO-3-NITROBENZOIC ACID
RARECHEM AL BO 0441
2,6-Difluoro-3-nitrobenzoic acid 98%
2,6-Difluoro-3-nitrobenzoicacid98%
2,6-Difluro-3-nitrobenzoic acid | [Molecular Formula]
C7H3F2NO4 | [MDL Number]
MFCD00119291 | [Molecular Weight]
203.1 | [MOL File]
83141-10-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
92-96°C | [Boiling point ]
335.5±42.0 °C(Predicted) | [density ]
1.661 | [storage temp. ]
Keep Cold | [form ]
powder to crystal | [pka]
1.48±0.29(Predicted) | [color ]
White to Light yellow | [InChI]
InChI=1S/C7H3F2NO4/c8-3-1-2-4(10(13)14)6(9)5(3)7(11)12/h1-2H,(H,11,12) | [InChIKey]
PDDHSNODMFIIRV-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=C(F)C=CC([N+]([O-])=O)=C1F | [CAS DataBase Reference]
83141-10-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant/Keep Cold | [HazardClass ]
IRRITANT | [HS Code ]
29163990 |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow solid | [Uses]
2,6-Difluoro-3-nitrobenzoic acid is a benzoic acid derivative that contains reactive substituent fluorine atoms and nitro groups in its molecular structure. The substance is mainly used as a reagent for organic synthesis or as a component of pharmaceutical intermediates. It is used in the synthesis of B-Raf kinase inhibitors, such as vemurafenib, which causes programmed cell death (apoptosis) in melanoma cell lines. In addition, it is used in the synthesis of fluoroquinolone antibacterial agents. |
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