| Identification | Back Directory | [Name]
7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one | [CAS]
846032-02-8 | [Synonyms]
PF-00217830
PF 00217830,PF00217830
7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
1,8-Naphthyridin-2(1H)-one, 3,4-dihydro-7-[4-[4-(1-naphthalenyl)-1-piperazinyl]butoxy]- | [Molecular Formula]
C26H30N4O2 | [MOL File]
846032-02-8.mol | [Molecular Weight]
430.54 |
| Hazard Information | Back Directory | [Uses]
F-00217830 is an agonist ofDopamine D2 receptor. PF-00217830 inhibits of spontaneous locomotor activity and 2,5-dimethoxy-4-iodoamphetamine-induced head twitches in rats[1]. | [References]
[1] Johnson DS, et al. Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder. Bioorg Med Chem Lett. 2011;21(9):2621-2625. DOI:10.1016/j.bmcl.2011.01.059 |
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