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850467-77-5

850467-77-5 Structure

850467-77-5 Structure
IdentificationBack Directory
[Name]

Benzamide, N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-4-phenoxy-
[CAS]

850467-77-5
[Synonyms]

WAY-641918
N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-4-phenoxybenzamide
Benzamide, N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-4-phenoxy-
[Molecular Formula]

C25H24N2O3
[MOL File]

850467-77-5.mol
[Molecular Weight]

400.47
Chemical PropertiesBack Directory
[Boiling point ]

665.5±55.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.26±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

TAO Kinase inhibitor 2 (Example 49) is a TAO Kinase inhibitor (IC50=between 50 and 500 nM). TAO Kinase inhibitor 2 also inhibits KIAA1361 and JIK with IC50s of 50-500 nM[1].
[References]

[1] Deborah Lynn Baly, et al. Tao kinase modulators and methods of use. Patent. WO2005040355.
Spectrum DetailBack Directory
[Spectrum Detail]

Benzamide, N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-4-phenoxy-(850467-77-5)1HNMR
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