ChemicalBook--->CAS DataBase List--->851785-21-2

851785-21-2

Request For Quotation
851785-21-2 Structure

851785-21-2 Structure
IdentificationBack Directory
[Name]

methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride
[CAS]

851785-21-2
[Synonyms]

Lifitegrast Intermediate 5
methyl (2S)-2-amino-3-(3-methylsulfonylphenyl)propanoate
3-(Methylsulfonyl)-L-phenylalanine methyl ester hydrochloride
METHYL (S)-2-AMINO-3-(3-(METHYLSULFONYL)PHENYL)PROPANOATE HCL
methyl (2S)-2-amino-3-(3-methanesulfonylphenyl)propanoate hydrochloride
(S)-Methyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride
methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride
[Molecular Formula]

C11H16ClNO4S
[MDL Number]

MFCD29037384
[MOL File]

851785-21-2.mol
[Molecular Weight]

293.767
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,Room Temperature
[Appearance]

White to off-white Solid
[InChI]

InChI=1/C11H15NO4S.ClH/c1-16-11(13)10(12)7-8-4-3-5-9(6-8)17(2,14)15;/h3-6,10H,7,12H2,1-2H3;1H/t10-;/s3
[InChIKey]

VUUYKOLKOIYVCR-MEQOOBBNNA-N
[SMILES]

C(C1C=CC=C(S(=O)(=O)C)C=1)[C@H](N)C(=O)OC.Cl |&1:11,r|
Questions And AnswerBack Directory
[Application]

(S)-2-amino-3-methylsulfonyl-phenylpropionate methyl ester hydrochloride can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical and pharmaceutical synthesis processes.
Spectrum DetailBack Directory
[Spectrum Detail]

methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride(851785-21-2)1HNMR
Hazard InformationBack Directory
[Synthesis]

L-Phenylalanine, 3-(methylsulfonyl)-N-[(phenylmethoxy)carbonyl]-, methyl ester

851785-26-7

methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

851785-21-2

Hydrogenation of the compound (CAS: 851785-26-7) as starting material was carried out in methanol (MeOH) by hydrogen ballooning with palladium carbon (Pd/C) as catalyst to give compound 8.4 in 98% yield. The product was confirmed by electrospray ionization mass spectrometry (ESI-MS) with a mass-to-charge ratio (m/z) of 258 ([M+H]+).

[References]

[1] Patent: WO2005/44817, 2005, A1. Location in patent: Page/Page column 92-93
851785-21-2 suppliers list
Company Name: Chengdu Miracle Pharmaceutical Co., Ltd.  Gold
Telephone: 028-86136736 19130631884
Website: www.mic-pharma.com
Company Name: Chengdu Focus Pharmaceutical Technology Co., Ltd.  Gold
Telephone: 028-64950838 17340131597
Website: https://www.chemicalbook.com/ShowSupplierProductsList30205/0_EN.htm
Company Name: BeiJing Hwrk Chemicals Limted  
Telephone: 0757-86329057 18934348241
Website: www.hwrkchemical.com/
Company Name: SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.  
Telephone: 21-33585366 13311639313
Website: http://www.shyrchem.com
Company Name: AstaTech (Chengdu) Pharma. Co., Ltd.  
Telephone: 15928766785 15928766785
Website: http://www.astabiochem.cn/
Company Name: DONGSHENG CHIRAL PHARMA  
Telephone: 15800326364 18051538752
Website: http://www.szchp.com/
Company Name: Taizhou Tongxin Bio-Tech Co., Ltd  
Telephone: 0523-86818997 18652728585
Website: https://www.allyrise.com
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-164-7117 18317119277
Website: www.bidepharm.com
Company Name: Shanghai SE Pharm Co., Ltd  
Telephone: 18112588827
Website: www.sepharm.com.cn
Company Name: Nanjing Duolong Bio-tech Co.,Ltd.  
Telephone: 18905173768
Website: http://www.dolonchem.com
Company Name: BEIJING EAGLE SKY PHARMATECH CO., LTD  
Telephone: 010-88755821 13911359480;18612220856
Website: http://www.eagleskypharmatech.com
Company Name: Shanghai Peiyang Chemical Co., Ltd.  
Telephone: +86 (21) 61919736
Website: www.chemicalbook.com/ShowSupplierProductsList16620/0_EN.htm
Company Name: Nanjing River Chemical Co., Ltd.  
Telephone: 13951936332 18305166317
Website: www.serpharm.cn
Company Name: skychemical Co.Ltd  
Telephone: 021-20960837,QQ1332204249
Website: http://www.skychemical.com
Company Name: Shanghai GL Peptide Ltd.  
Telephone: +86-21-61263310 13764994101
Website: www.chemicalbook.com/supplier/10480342/
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: Amatek Scientific Co. Ltd.  
Telephone: 0512-56316828 400-867-5858;400-867-5858
Website: http://www.amateksci.com
Company Name: LinkChem Technology Co., Ltd.  
Telephone: 021-58950110 13124863828
Website: www.linkchem.cn
Tags:851785-21-2 Related Product Information
82278-73-7 1289646-76-9 1194550-59-8 851784-90-2 851785-21-2 1289646-93-0 1270093-99-6 77095-51-3 1194550-59-8 851784-82-2 1025967-78-5