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861224-48-8

861224-48-8 Structure

861224-48-8 Structure
IdentificationBack Directory
[Name]

(8-benzoyl-5-oxo-2,3,6,7-tetrahydro-5H-[1,3]thiazolo[3,2-a]pyridin-6-yl)acetic acid
[CAS]

861224-48-8
[Synonyms]

5H-Thiazolo[3,2-a]pyridine-6-acetic acid, 8-benzoyl-2,3,6,7-tetrahydro-5-oxo-
(8-benzoyl-5-oxo-2,3,6,7-tetrahydro-5H-[1,3]thiazolo[3,2-a]pyridin-6-yl)acetic acid
[Molecular Formula]

C16H15NO4S
[MOL File]

861224-48-8.mol
[Molecular Weight]

317.36
Chemical PropertiesBack Directory
[Boiling point ]

580.2±50.0 °C(Predicted)
[density ]

1.44±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

4.21±0.10(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1].
[References]

[1] Xuehui Long, et al. Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity. Nat Immunol. 2024. DOI:10.1038/s41590-024-01746-8
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