| Identification | Back Directory | [Name]
Chymase-IN-1 | [CAS]
862090-74-2 | [Synonyms]
Chymase-IN-1
Phosphonic acid, P-[1-(5-chlorobenzo[b]thien-3-yl)-2-(2-naphthalenylamino)-2-oxoethyl]- | [Molecular Formula]
C20H15ClNO4PS | [MDL Number]
MFCD30533332 | [MOL File]
862090-74-2.mol | [Molecular Weight]
431.83 |
| Chemical Properties | Back Directory | [density ]
1.583±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.56±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Chymase-IN-1, is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase | [in vivo]
Chymase-IN-1 exhibits low oral bioavailability in rats (F=3%; oral t1/2=1.8 h)[1]. |
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